针灸对功能性消化不良伴睡眠障碍的应用价值

发布时间：2018-04-26 08:00

本文选题：针灸 + 胃功能　；参考：《辽宁中医杂志》2017年02期

【摘要】：目的:探讨针灸对功能性消化不良伴睡眠障碍的治疗效果。方法:选取2013年5月—2015年5月在本科接受治疗的80例功能性消化不良伴睡眠障碍患者为研究对象,随机分为观察组和对照组,每组各40例,对照组给予药物治疗,观察组在药物治疗的基础上给予针灸治疗,6 d为1个疗程,两组患者均给予两个疗程的治疗。疗程结束后,对两组患者的PSQI和SF-36得分进行比较;比较治疗后两组患者神经肽和胃动素的差异;比较治疗前后两组患者IL-1、IL-6以及TNF水平的差异。结果:治疗前两组患者PSQI积分差异无统计学意义,治疗后观察组较对照组降低更为明显;治疗后两组患者SF-36得分均增高,且观察组高于对照组,差异具有统计学意义;治疗两组患者的前神经肽和胃动素水平差异无统计学意义,治疗后,观察组患者神经肽及胃动素水平显著高于对照组;治疗后观察组组患者血清中IL-1、IL-6及TNF浓度高于对照组(P0.05)。结论:针灸可通过促进神经肽和胃动素的分泌改善功能性消化不良患者的肠胃功能,同时通过促进患者体内IL-1、IL-6及TNF的升高改善睡眠,提高患者的生活质量。
[Abstract]:Objective: to investigate the therapeutic effect of acupuncture and moxibustion on functional dyspepsia with sleep disorder. Methods: from May 2013 to May 2015, 80 patients with functional dyspepsia with sleep disorder were randomly divided into observation group (n = 40) and control group (n = 40). The observation group was treated with acupuncture and moxibustion for 6 days on the basis of drug therapy, and both groups were given two courses of treatment. After the course of treatment, the PSQI and SF-36 scores of the two groups were compared; the differences of neuropeptide and motilin in the two groups were compared after treatment; the levels of IL-6 and TNF in the two groups were compared before and after treatment. Results: there was no significant difference in PSQI score between the two groups before and after treatment, the SF-36 score of the observation group was significantly lower than that of the control group, and the SF-36 score of the observation group was higher than that of the control group, and the difference was statistically significant. There was no significant difference in the levels of anterior neuropeptide and motilin between the two groups. After treatment, the levels of neuropeptide and motilin in the observation group were significantly higher than those in the control group, and the serum levels of IL-1IL-6 and TNF in the observation group were higher than those in the control group (P 0.05). Conclusion: acupuncture and moxibustion can improve the gastrointestinal function of patients with functional dyspepsia by promoting the secretion of neuropeptide and motilin. At the same time, it can improve sleep and improve the quality of life by promoting the increase of IL-1- 6 and TNF in patients with functional dyspepsia.
【作者单位】：宜昌中心人民医院三峡坝区分院;
【分类号】：R246.6

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