朝医清心莲子汤治疗血管性痴呆患者86例的临床观察

发布时间：2018-04-27 11:15

本文选题：清心莲子汤 + 血管性痴呆　；参考：《时珍国医国药》2017年06期

【摘要】：目的观察朝医清心莲子汤提高血管性痴呆患者智能水平的临床疗效。方法根据血管性痴呆诊断标准,将符合血管性痴呆诊断的86例患者随机分为对照组和治疗组,每组43例;对照组用盐酸多奈哌齐改善痴呆症状,治疗组在盐酸多奈哌齐治疗的基础上加用朝医清心莲子汤治疗,两组均治疗20周。评价两组治疗前后简易智能精神状态评估量表(MMSE)、日常生活功能量表(ADL)血管性痴呆量表(DSVD),采用经颅多普勒仪检测治疗前后ACA、MCA平均血流速度和搏动指数,治疗后疗效比较。结果治疗后两组患者MMSE、ADL、DSVD评分均较治疗前明显提高(P0.05),ACA、MCA平均血流速度和搏动指数治疗组较对照组提高更明显(P0.05),服药20周后,治疗组有效率88.4%,对照组有效率74.4%。结论清心莲子汤结合盐酸多奈哌齐治疗,比单纯用盐酸多奈哌齐治疗有更好的疗效,可提高智能水平,改善脑血流量和速度,是血管性痴呆防治中值得推广的有效方剂。
[Abstract]:Objective to observe the clinical effect of Chaoyi Qingxin Lianzi decoction (QXL decoction) on improving the intelligence level of vascular dementia patients. Methods according to the diagnostic criteria of vascular dementia, 86 patients with vascular dementia were randomly divided into control group (n = 43) and treatment group (n = 43). The treatment group was treated with Qing Xin Lianzi decoction on the basis of Donepezil Hydrochloride, both groups were treated for 20 weeks. Objective: to evaluate the simple mental state assessment scale (MMSE) and ADL (ADL) vascular dementia scale before and after treatment in two groups. The average blood flow velocity and pulsatile index of ACAMCA before and after treatment were measured by transcranial Doppler instrument, and the curative effect was compared after treatment. Results after treatment, the average blood flow velocity and pulsatile index of the two groups were significantly higher than those of the control group. After 20 weeks of treatment, the effective rate of the treatment group was 88.4 and that of the control group was 74.4. Conclusion Qingxinlianzi decoction combined with Donepezil Hydrochloride has a better curative effect than that of Donepezil Hydrochloride alone. It can improve intelligence level, improve cerebral blood flow and speed. It is an effective prescription worth popularizing in the prevention and treatment of vascular dementia.
【作者单位】：延边大学中医学院;
【基金】：吉林省中医药科技项目(No.413080006)
【分类号】：R29

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