针刺内关穴对心肌缺血中枢神经调节作用的研究进展

发布时间：2018-04-28 19:39

本文选题：内关 + 心肌缺血　；参考：《中国中医基础医学杂志》2017年04期

【摘要】：大量的临床实践证实了"心胸内关谋"这一经典论述,研究内关穴治疗心脏疾病的作用机制有利于揭示经穴脏腑相关特异性的机理。近年来,针刺内关穴抗心肌缺血作用机制的研究颇多,除了传统的心电图、病理学组织切片、B超外,还采用分子生物学技术、膜片钳技术、脑功能成像以及PET成像等技术来探讨针刺对脑的经典神经递质、神经激素、神经元代谢等影响,从器官、系统到细胞、受体、细胞核、基因、蛋白质分子等不同的层次上,为针刺抗心肌缺血的中枢神经调节机制提供大量的实验基础,故针对近年来针刺内关穴抗心肌缺血的中枢神经调节作用研究进展加以讨论。
[Abstract]:A large number of clinical practices have confirmed the classic exposition of "Heart, chest and Internal Medicine". Studying the mechanism of the treatment of heart disease at Neiguan is helpful to reveal the specific mechanism of the viscera related to the acupoints. In recent years, there have been many studies on the mechanism of acupuncture at Neiguan point on myocardial ischemia. In addition to traditional electrocardiogram, histopathological sections, B-ultrasound, molecular biology and patch-clamp techniques are also used. Brain function imaging and PET imaging are used to explore the effects of acupuncture on the classical neurotransmitters, neurohormones, neuronal metabolism, and so on, from organs, systems to cells, receptors, nuclei, genes, protein molecules and so on. This paper provides a large amount of experimental basis for the central nervous regulation mechanism of acupuncture on myocardial ischemia, so the research progress on the central nervous regulatory effect of acupuncture at Neiguan point on myocardial ischemia in recent years is discussed.
【作者单位】：湖北中医药大学针灸骨伤学院针灸治未病湖北省协同创新中心;
【基金】：国家自然科学基金资助项目(81403460,81273865) 湖北省自然科学基金资助项目(2016CFB221) 湖北中医药大学校级课题(XJ2014KJ003)
【分类号】：R245

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