清热散结汤治疗结节性红斑的临床观察

发布时间：2018-04-30 11:20

本文选题：结节性红斑 + 湿热瘀阻证　；参考：《黑龙江中医药大学》2016年硕士论文

【摘要】：目的：观察清热散结汤治疗结节性红斑(湿热瘀阻证)的临床疗效从而研究清热散结汤对疾病皮损,临床症状的疗效。方法：入选病例均来自2014年12月一2015年12月黑龙江中医药大附属第一医院皮肤科,将符合标准的72例患者,随机分为2组,治疗组完成治疗35例,对照组完成治疗34例,其中3例在观察中脱落。治疗组给予中药方剂清热散结汤,饭后服；对照组给予肿痛安胶囊(每次2粒,一日3次,饭后30分钟温水送服),1个疗程2周,观察2个疗程。疗程结束后,观察患者结节数量、红斑颜色、疼痛程度,结节平均直径的变化。结果：临床研究显示,治疗2个疗程后,治疗组总有效率94.30%,对照组总有效率82.35%,治疗组总有效率明显优于对照组总有效率,经统计学分析, (P0.05),两者有显著性差异。治疗组能明显改善结节的数量、颜色、疼痛、平均直径等症状。结论:1、清热散结汤能够有效改善结节性红斑(湿热瘀阻证)治疗前后的皮损积分。2、清热散结汤是治疗结节性红斑(湿热瘀阻证)安全有效的方剂。
[Abstract]:Objective: to observe the clinical effect of Qingre Sanjie decoction on nodular erythema (damp-heat stasis syndrome) and to study the curative effect of Qingre Sanjie decoction on skin lesions and clinical symptoms. Methods: all the patients were selected from the Department of Dermatology of the first affiliated Hospital of Heilongjiang traditional Chinese Medicine from December 2014 to December 2015. The 72 patients who met the standard were randomly divided into two groups: the treatment group (n = 35) and the control group (n = 34). Among them, 3 cases dropped off during observation. The treatment group was given traditional Chinese medicine prescription Qingre Sanjie decoction after meals, while the control group was given two capsules of Gongtong an (2 capsules per day, 3 times a day, 30 minutes after meal), a course of treatment for 2 weeks, observation of two courses of treatment. At the end of the course, the number of nodules, the color of erythema, the degree of pain and the mean diameter of nodules were observed. Results: the clinical study showed that after two courses of treatment, the total effective rate of the treatment group was 94.30%, the total effective rate of the control group was 82.35, the total effective rate of the treatment group was obviously superior to the total effective rate of the control group, and the statistical analysis showed that the total effective rate of the treatment group was 94.30%, and the total effective rate of the control group was 82.35%. The treatment group significantly improved the number, color, pain and mean diameter of nodules. Conclusion: 1. Qingre Sanjie decoction can effectively improve the integral of skin lesion of nodular erythema (damp-heat stasis syndrome) before and after treatment. Qingre Sanjie decoction is a safe and effective prescription for the treatment of nodular erythema (damp-heat stasis syndrome).
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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