董氏奇穴皮内针治疗寒湿凝滞型原发性痛经的临床观察
发布时间:2018-05-04 17:43
本文选题:董氏奇穴 + 皮内针 ; 参考:《广州中医药大学》2017年硕士论文
【摘要】:目的:通过皮内针埋针董氏奇穴与西药芬必得治疗寒湿凝滞型原发性痛经的对照研究,分析评价皮内针埋针董氏奇穴疗法对寒湿凝滞型原发性痛经的有效性及安全性。方法:本课题病例来源于惠州市大亚湾区第一中学高中部校医室就诊患者,收集符合纳入标准病例60例,脱落2个病例,研究结束时共收入统计分析的病例共58例,其中皮内针埋针董氏奇穴组30例和西药芬必得组28例。治疗组选用董氏奇穴中妇科穴(双穴)及还巢穴(双穴交替使用),采用图钉型皮内针(华佗牌,格是中0.25X1.3mm)于痛经发作时埋针,埋针时间为2天。对照组选用芬必得布洛芬缓释胶囊进行治疗。药品规格为0.3*20粒/盒。受试者每次服药1粒,一日两次(清晨傍晚各一次),饭后服药。痛经发作时服药,服药2天。本研究设定1个月经周期为1个疗程,均连续完成3个月经周期的治疗。研究者分别在治疗前、疗程1结束后、疗程2结束后、疗程3结束后、疗程结束后随访1个月这个5个节点选用视觉模拟评分量表、痛经症状评分量表作为疗效观察指标进行观察记录。同时,研究中需谨慎观察并记录研究中的可能出现的不良反应或副作用。研究结束后,将所有记录数值录入统计分析SPSS软件包中,进行数据的统计分析。计量资料根据方差齐性选取t检验或秩和检验;双侧检验,检验水平设为a=0.05。结果:治疗组在治疗前后VAS评分如下:治疗前7.17±1.21;疗程1结束后6.13±1.17;疗程2结束后5.30±0.75;疗程3结束后4.73±0.79;疗程结束后随访1个月5.87±0.94;治疗组治疗前与各疗程结束后对比,对应的t值分别为:31.000、14.000、14.250、8.963;对应P值均为0.000。对照组在治疗前后VAS评分如下:治疗前7.11±1.29;疗程1结束后5.46±1.00;疗程2结束后4.39±0.83;疗程3结束后3.32±0.98;随访1个月6.57±1.73;对照组治疗前与各疗程结束后对比,对应的t值分别为12.813、16.016、20.139、4.448;对应的P值均为0.000。治疗组与对照组在治疗前与每疗程结束后及随访1个月的组间对比,对应t值分别为:0.182、2.338、4.369、6.064、-2.268;对应P值分别为:0.856、0.023、0.000、0.000、0.028。治疗组在治疗前后痛经症状评分如下:治疗前14.10±3.43;疗程1结束后11.27±3.10;疗程2结束后9.40±2.46;疗程3结束后8.70±2.41;疗程结束后随访1个月10.30±3.21;治疗组治疗前与各疗程结束后对比,对应的t值分别为:19.607、19.547、21.060、42.982;对应P值均为0.000。对照组在治疗前后痛经症状评分如下:治疗前14.29±3.47;疗程1结束后11.18±2.47;疗程2结束后9.14±1.72;疗程3结束后7.57±1.50;随访1个月12.29±2.67;对照组治疗前与各疗程结束后对比,对应的t值分别为13.395、13.049、15.088、9.165;对应的P值均为0.000。治疗组与对照组在治疗前与每疗程结束后及随访1个月的组间对比,对应 t 值分别为:-0.205、0.119、0.465、2.156、-2.555;对应P值分别为:。0.838、0.905、0.644、0.036、0.013。皮内针埋针董氏奇穴疗法及芬必得治疗寒湿凝滞型原发性痛经在治疗前后,基于VAS评分、痛经症状评分的组内比较,有统计学差异(P0.05)。同时,在治疗结束后的VAS评分及痛经症状评分对比中,对照组评分下降更多,且两组差异有统计学意义(P0.05)。但是在随访1个月,对照组的评分回升比治疗组更多,且两组对比差异有统计学意义(P0.05)。结论:皮内针埋针董氏奇穴与西药芬必得均可降低青春期原发性痛经患者的视觉模拟评分量表(VAS)评分和痛经症状评分表评分。在近期疗效上西药芬必得明显优于皮内针埋针董氏奇穴。但是在随访停止治疗后1个月时,西药芬必得组评分出现较大的回升,皮内针组评分回升幅度较小,因此在本研究中皮内针埋针董氏奇穴远期疗效优于西药芬必得。本研究治疗组和对照组在研究开展治疗前后及研究治疗期间都没有出现不良反应。
[Abstract]:Objective: To evaluate the efficacy and safety of Dong Shi point therapy for cold dampness and stagnation of primary dysmenorrhea by intradermal needle burial needle and Western medicine finvert in treating primary dysmenorrhea. Methods: the case was derived from the school medical room of high school in the first middle school in Dayawan District, Huizhou. A total of 58 cases were collected, including 60 cases of standard cases, 2 cases, and 58 cases of total income statistical analysis at the end of the study. Among them, 30 cases of intradermal needle burial acupuncture point group and 28 western medicine finch group were used. The treatment group was used in Dong's acupoint of gynecologic acupoints (double points) and nesting points (double acupoints alternately used), and tack type intradermal needles (Hua Tuo brand). In the case of middle 0.25X1.3mm) the needle was buried at 2 days. The control group was treated with finp Ibuprofen Sustained-Release Capsules. The size of the drug was 0.3*20 granule / box. The subjects took 1 tablets each time, two times a day (each morning in the morning), after meals, taking medicine and taking medicine for 2 days. The study set up 1 menstrual cycles for 1. After the course of treatment, 3 menstrual cycles were completed. After the treatment, the researchers were treated after the treatment of 1, after the end of the course of treatment, after the end of the course of treatment, after the end of the course of treatment, after the end of the course of treatment, after the end of the course of 3, after the end of the course was followed up for 1 months, the 5 nodes selected the visual analogue scale, the dysmenorrhea symptom scale was observed as the observation index of the curative effect. Meanwhile, the study should be cautious. Check and record the possible adverse reactions or side effects in the study. After the study, all the records were recorded in the statistical analysis SPSS software package to carry out the statistical analysis of the data. The measurement data were selected according to the homogeneity of variance t test or rank sum test; the bilateral test and the test water were set to a=0.05. results: the treatment group was evaluated before and after the treatment of VAS. The scores were as follows: 7.17 + 1.21 before the treatment, 6.13 + 1.17 after the end of the course 1, 5.30 + 0.75 after the treatment of the course of treatment, 4.73 + 0.79 after the end of the course of treatment, and 4.73 + 0.79 after the end of the course of treatment; the treatment group was compared with the end of each course after the course of treatment. The corresponding T values were respectively 31.000,14.000,14.250,8.963; the corresponding P values were all VAS before and after the treatment in the 0.000. control group. The scores were as follows: 7.11 + 1.29 before the treatment, 5.46 + 1 after the end of the course of treatment, 4.39 + 0.83 after the treatment of the course of treatment, 3.32 + 0.98 after the end of the course of the course of treatment, 1 months of 6.57 + 1 months follow-up, and the corresponding T values of the control group were 12.813,16.016,20.139,4.448 before the treatment, and the corresponding P values were both before the treatment and each treatment in the 0.000. treatment group and the control group. After 1 months of follow-up, the corresponding T values were 0.182,2.338,4.369,6.064 and -2.268, and the corresponding P values were as follows: the symptoms of dysmenorrhea before and after treatment in 0.856,0.023,0.000,0.000,0.028. treatment group were as follows: 14.10 + 3.43 before treatment, 11.27 + 3.10 after the end of the course of treatment, 9.40 + 2.46 after the end of the course 2, and 8.70 + 2.41 after the end of 3 course of treatment; After the course of treatment, follow up 1 months 10.30 + 3.21, the treatment group before treatment and after the end of the treatment, the corresponding T values are: 19.607,19.547,21.060,42.982, the corresponding P values are 0.000. control group before and after treatment of dysmenorrhea symptom score as follows: before treatment 14.29 + 3.47, 11.18 + 2.47 after the end of the course of treatment, 9.14 + 1.72 after the end of the course of treatment, 3 end of course 3 end. After 7.57 + 1.50, the follow-up was 1 months 12.29 + 2.67, the control group was compared with the end of each course after treatment, the corresponding t value was 13.395,13.049,15.088,9.165, and the corresponding P values were compared between the 0.000. treatment group and the control group before and after each course and followed up for 1 months. The corresponding T values were -0.205,0.119,0.465,2.156, -2.555, respectively. The corresponding P values were:.0.838,0.905,0.644,0.036,0.013. intradermal needle burial acupuncture point therapy and the treatment of cold dampness and stagnation of primary dysmenorrhea before and after treatment, based on VAS score, compared with the scores of dysmenorrhea, there were statistical differences (P0.05). At the same time, the comparison of the VAS score and the dysmenorrhea symptom score after the end of the treatment was compared. The score of the group decreased more, and the difference between the two groups was statistically significant (P0.05). But in the 1 months of follow-up, the score of the control group was higher than that in the treatment group, and the difference between the two groups was statistically significant (P0.05). Conclusion: the visual analogue scale of the patients with primary dysmenorrhea in puberty can be reduced by the intradermal needle burial needle and the western medicine finp (V AS) score and dysmenorrhea score. In the near future, the western medicine Finn must be significantly better than the intradermal needle Dong Shiqi point. But in the 1 months after the cessation of treatment, the score of the western medicine Finn must have a greater recovery, and the score of the intradermal acupuncture group is smaller. Therefore, the long term effect of the intradermal needles in this study is in this study. There was no adverse reaction in the treatment group and the control group before and after the treatment.
【学位授予单位】:广州中医药大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R246.3
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本文编号:1843966
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