2型糖尿病中医证型与颈动脉内膜中层厚度、人血浆脂蛋白磷脂酶A2、同型半胱氨酸及病程的相关性研究

发布时间：2018-05-05 13:34

本文选题：2型糖尿病 + 中医证型　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:研究2型糖尿病中医证型与颈动脉内膜中层厚度、人血浆脂蛋白磷脂酶A2、同型半胱氨酸及病程之间的关系,并对其进行了临床观察和分析,提高了2型糖尿病的中医辨证分型的科学性和客观性,同时也提供了更多临床参考依据。方法:实验组为100例,正常对照组为20例,将实验组100例患者按照中医辨证的原则分为阴虚热盛、气阴两虚、气滞血瘀和痰湿阻滞四型,分别观察四组的颈动脉内膜中层厚度、人血浆脂蛋白磷脂酶A2、同型半胱氨酸及患者病程之间的相关性,并进行统计学的分析和处理。结果:2型糖尿病中医证型颈动脉内膜中层厚度、人血浆脂蛋白磷脂酶A2、同型半胱氨酸水平存在显著差异性,并且在疾病的不同发展阶段中也存在明显差异性。结论:2型糖尿病在疾病发展过程中,呈现阴虚热盛、气阴两虚、气滞血瘀及痰湿阻滞的趋势变化,痰湿与血瘀始终贯穿疾病发展阶段。
[Abstract]:Objective: To study the relationship between the TCM syndrome type of type 2 diabetes and carotid intima media thickness, the relationship between human plasma lipoprotein phospholipase A2, homocysteine and course of disease, and the clinical observation and analysis to improve the scientificity and objectivity of TCM syndrome differentiation of type 2 diabetes mellitus, and also provide more clinical reference basis. 100 cases in the experimental group and 20 cases in the normal control group, 100 patients in the experimental group were divided into four types: Yin deficiency heat, Qi and yin deficiency, qi stagnation and blood stasis and phlegm dampness block. The thickness of the middle layer of the carotid artery intima of the four groups, the relationship between the plasma lipoprotein phospholipase A2, the homocysteine and the course of disease in the human plasma was observed. Statistical analysis and treatment. Results: the thickness of the carotid intima media in the TCM syndrome type of type 2 diabetes, the plasma lipoprotein phospholipase A2, the homocysteine level was significantly different, and there was a significant difference in the different stages of the disease. Conclusion: 2 type of glycan disease in the process of disease development, showing Yin deficiency hot, Qi, Qi Yin two deficiency, qi stagnation, blood stasis and phlegm dampness trend changes, phlegm dampness and blood stasis throughout the disease development stage.

【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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