益气养阴法治疗眼底出血的临床疗效观察

发布时间：2018-05-08 12:44

本文选题：益气养阴 + 眼底出血　；参考：《辽宁中医药大学》2017年硕士论文

【摘要】：目的:通过观察益气养阴法参与治疗眼底出血的临床疗效,探索中医药控制眼底出血的有效方法。临床资料与方法:将2016年8月至2017年1月就诊于沈阳何氏眼科医院气阴两虚型眼底出血的患者共计57例(69眼)应用随机数字表法随机分为两组:对照组28例(34眼)和治疗组29例(35眼)。对照组予以基础治疗(控制血压,血糖,血脂等)、口服卵磷脂络合碘片。治疗组在对照组处置的基础上,给予我院自制益气养阴的止血汤早晚温服。观察并记录两组患者治疗前后的视力变化、眼底出血面积、黄斑OCT平均厚度、中医证候积分等项,并对两组患者进行比较做统计学分析评价。结果:1.总体疗效:治疗前与治疗后一个月后比较,对照组的总有效率为64.47%,治疗组为82.86%,经统计分析差异具有统计学意义(P0.05),止血汤辅助治疗眼底出血疗效更佳。2.视力疗效:治疗一个月后两组视力均有提高,且治疗组优于对照组(P0.05)。3.出血面积吸收:治疗一个月后两组出血面积均减少,且治疗组优于对照组(P0.01)。4.黄斑OCT平均厚度:治疗一个月后两组黄斑OCT平均厚度均有所降低,治疗组优于对照组,但差异无统计学意义(P0.05)。5.中医证候积分:治疗一个月后治疗组各项中医证候积分较前改变,治疗组优于对照组(P0.01)。6.中医证候疗效:对照组有效率为25%,治疗组有效率为82.75%,治疗组优于对照组(P0.01)。7.糖尿病视网膜病变与视网膜静脉阻塞比较:治疗组内视网膜静脉阻塞的疗效好于糖尿病视网膜病变,但是差异不具有统计学意义(P0.05)。结论:本次疗效观察中未出现不良反应,止血汤参与治疗气阴两虚型眼底出血具有良好的临床疗效,证明止血汤辅助眼底出血相关疾病的疗效优于单纯西药组,总有效率高达82.86%。止血汤有助于眼底出血的吸收、水肿的吸收、视力的改善,提高患者的满意度,中西医结合治疗眼底出血值得临床推广应用。
[Abstract]:Objective: to explore the effective method of traditional Chinese medicine (TCM) to control fundus hemorrhage by observing the clinical effect of nourishing qi and nourishing yin in the treatment of fundus hemorrhage. Clinical data and methods: a total of 57 patients (69 eyes) with ocular fundus hemorrhage of Qi and Yin deficiency type from August 2016 to January 2017 were randomly divided into two groups: control group (28 cases, 34 eyes) ) and treatment group (29 cases, 35 eyes). The control group was treated with basic treatment (blood pressure, blood glucose, blood lipid, etc.), oral lecithin complex iodine tablets. On the basis of the control group, the treatment group was given the self-made Zhixue decoction for supplementing qi and nourishing yin in the morning and evening. The changes of visual acuity, the area of fundus hemorrhage, the mean thickness of macular OCT, and the score of TCM syndromes were observed and recorded before and after treatment. The result is 1: 1. The total effective rate was 64.47 in the control group and 82.86 in the treatment group. The difference was statistically significant (P 0.05). The curative effect of Zhixue decoction in the treatment of ocular fundus hemorrhage was better than that in the control group. Visual acuity: one month after treatment, the visual acuity of both groups were improved, and the treatment group was superior to the control group (P 0.05). 3. Haemorrhage area absorption: after one month of treatment, the haemorrhage area of both groups was decreased, and the treatment group was superior to the control group (P 0.01). 4. Mean thickness of macular OCT: after one month of treatment, the mean thickness of macular OCT in both groups was lower than that in control group, but the difference was not statistically significant (P 0.05). TCM syndromes integral: after one month of treatment, the TCM syndrome integral of the treatment group changed more than that of the former, and the treatment group was superior to the control group (P 0.01g. 6). The curative effect of TCM syndrome: the effective rate of the control group was 25g, the effective rate of the treatment group was 82.75m, the treatment group was superior to the control group (P0.01g. 7). Comparison of diabetic retinopathy and retinal vein occlusion: the therapeutic effect of retinal vein occlusion in the treatment group was better than that in diabetic retinopathy, but the difference was not statistically significant (P 0.05). Conclusion: there is no adverse reaction in this curative effect observation. Zhixue decoction has good clinical effect in treating ocular fundus hemorrhage with deficiency of Qi and Yin. It is proved that Zhixue decoction is superior to western medicine group in assisting ocular fundus hemorrhage related diseases, and the total effective rate is as high as 82.86. Zhixue decoction is helpful to the absorption of fundus hemorrhage, the absorption of edema, the improvement of visual acuity and the improvement of patients' satisfaction.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R276.7

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