推拿手法联合跑台训练对坐骨神经延期缝合大鼠神经再生的效果

发布时间：2018-05-08 13:58

本文选题：坐骨神经 + 神经再生　；参考：《中国康复理论与实践》2017年11期

【摘要】：目的探讨推拿手法联合跑台训练对坐骨神经横断伤延期外膜修复后促进神经再生的效果。方法 60只Sprague-Dawley大鼠随机等分为对照组、模型组和治疗组。后两组建立坐骨神经横断伤延期外膜缝合模型,治疗组给予捏法推拿及跑台训练,每天1次。分别于干预后1个月、2个月各取10只大鼠检测坐骨神经运动神经传导速度(MCV)、再生神经轴突数及施万细胞数,电镜观察超微结构。结果与模型组比较,治疗组MCV在干预后2个月加快(P0.05),轴突数无显著性差异(P0.05),施万细胞数增加(P0.05),电镜下损伤较轻。结论推拿手法联合跑台训练可促进损伤的周围神经再生。
[Abstract]:Objective to investigate the effect of massage combined with treadmill training on promoting nerve regeneration after delayed repair of epineurium in sciatic nerve transection. Methods 60 Sprague-Dawley rats were randomly divided into control group, model group and treatment group. The model of delayed epineurium suture of sciatic nerve transection was established in the latter two groups, and the treatment group was treated with kneading massage and treadmill training once a day. The motor nerve conduction velocity of sciatic nerve, the number of regenerated nerve axons and Schwann cells were measured in 10 rats at 1 month and 2 months after intervention, and the ultrastructure of sciatic nerve was observed by electron microscope. Results compared with the model group, the MCV of the treatment group accelerated P0.05 after 2 months of intervention, the number of axons had no significant difference (P0.05A), the number of Schwann cells increased P0.05A, and the injury was mild under electron microscope. Conclusion Massage manipulation combined with treadmill training can promote the regeneration of injured peripheral nerve.
【作者单位】：上海中医药大学附属岳阳中西医结合医院推拿科;上海中医药大学康复医学院;
【基金】：国家自然科学基金面上项目(No.30973806;No.81373764);国家自然科学基金青年基金项目(No.81603713)
【分类号】：R244.1

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