电针治疗脑卒中后认知障碍的系统评价

发布时间：2018-05-08 22:11

  本文选题：脑卒中 + 认知障碍　； 参考：《中国针灸》2017年10期

【摘要】：目的:系统评价电针治疗脑卒中后认知障碍(post-stroke cognitive impairment,PSCI)的疗效与安全性。方法:计算机检索中国知网数据库(CNKI)、中国生物医学文献数据库(CBM)、万方数据库(WanFang)、维普全文期刊数据库(VIP)、PubMed及The Cochrane library数据库中有关电针治疗PSCI的所有随机对照试验(randomized control trials,RCTs),检索时间为建库至2016年10月。由2名研究者独立地进行文献筛选与资料提取,采用Cochrane系统评价手册方法对纳入研究进行质量评价,采用RevMan 5.3软件进行Meta分析。结果:总共纳入14项RCTs,合计896例PSCI患者。Meta分析显示,电针组在改善PSCI患者简易精神状态检查量表(MMSE)积分[MD=1.78,95%CI(0.24,3.32),P=0.02]、蒙特利尔认知评定量表(Mo CA)积分[MD=1.92,95%CI(0.96,2.88),P0.000 1]、P 300潜伏期[MD=-11.01,95%CI(-18.91,-3.11),P=0.000 6]、P 300波幅[MD=1.56,95%CI(1.14,1.98),P0.00001]、Fugl-Meyer运动功能量表(FMA)积分[MD=10.74,95%CI(2.67,18.82),P=0.009]、临床疗效[RR=1.37,95%CI(0.98,1.91),P=0.06]方面优于对照组;在日常生活能力的改善方面,电针组疗效与对照组比较差异无统计学意义[MD=6.38,95%CI(-2.41,15.18),P=0.15]。结论:本次系统评价证实电针治疗PSCI有效且安全性较可靠,电针可改善PSCI患者认知功能、运动功能,但由于本次纳入文献质量较低,仍需更多设计合理的多中心RCT研究加以验证。
[Abstract]:Objective: to evaluate the efficacy and safety of electroacupuncture (EA) in the treatment of post-stroke cognitive impairment (PSCI) after stroke. Methods: a computerized search for CNKI, CBM, Wan Fang, Weip full-text journal database, and all randomized controlled trials on electroacupuncture for PSCI were conducted in the database of China Web site, China Biomedical Literature Database, Wanfang Journal Database, Weip Full-Text Journal Database, and all randomized controlled trials on electroacupuncture treatment of PSCI. Trialsl RCTs, the retrieval time is until October 2016. Two researchers independently carried out literature screening and data extraction, using the Cochrane system evaluation manual method to evaluate the quality of the inclusion study, and using RevMan 5.3 software to carry out Meta analysis. Results: a total of 14 RCTs were included, a total of 896 patients with PSCI. Meta-analysis showed that, 鐢甸拡缁勫湪鏀瑰杽PSCI鎮ｈ，

本文编号：1863291