清肺化饮逐痹颗粒治疗肺痹邪盛痹重期(寒饮伏肺,肺络痹阻)的临床疗效观察
本文选题:间质性肺疾病 + 清肺化饮逐痹颗粒 ; 参考:《长春中医药大学》2016年硕士论文
【摘要】:目的:本课题从脏腑间生、克、乘、侮关系出发,通过观察应用清肺化饮逐痹颗粒治疗肺痹邪盛痹重期(寒饮伏肺,肺络痹阻)的临床疗效,来验证该药的临床疗效,同时也可以进一步揭示该病的机理,从而为广大患者带来希望。方法:选取60例来自长春中医药大学附属医院肺病科符合入组条件的患者,将其随机分为观察组和对照组,每组各30例,让观察组患者服用清肺化饮逐痹颗粒治疗、对照组患者服用强的松片维持治疗。通过观察治疗前后症状的改变,来明确两组治疗效果的不同。结果:经过1个月的临床观察研究,观察组与对照组的总有效率分别为86.7%、70%,两组间总有效率(P=0.3070.05),将两组数据对比后可以看出,观察组与对照组对该病主症的治疗效果无明显差异,但对次要症状的改善,观察组要优于对照组,比如关节疼痛,头面浮肿等。结论:经过疗效观察对比后发现,应用清肺化饮逐痹颗粒治疗肺痹邪盛痹重期(寒饮伏肺,肺络痹阻)证在缓解咳嗽、咳痰、喘促等症状时与应用激素疗效相同,但在缓解关节疼痛,及肢体头面浮肿等方面,要优于激素治疗,而且还具有用药方便,副反应少,便于携带等优点,具有广泛的应用和推广价值。
[Abstract]:Objective: from the relationship between viscera and viscera, to verify the clinical effect of Qingfei Huayin Zubi granule in treating the serious stage of lung arthralgia, such as cold drink and latent lung, lung collaterals obstruction, etc, in order to verify the clinical effect of this medicine. At the same time, it can also further reveal the mechanism of the disease, thus bringing hope to the majority of patients. Methods: sixty patients from lung disease department of Changchun University of traditional Chinese Medicine were randomly divided into observation group and control group with 30 cases in each group. The patients in observation group were treated with Qingfei Yinzubi granule. The patients in the control group were treated with prednisone tablets. By observing the changes of symptoms before and after treatment, the difference of therapeutic effect between the two groups was made clear. Results: after one month of clinical observation, the total effective rates of the observation group and the control group were 86.7 and 70, respectively, and the total effective rate of the two groups was 0.3070.050.After comparing the data of the two groups, it can be seen that there was no significant difference in the therapeutic effect between the observation group and the control group for the main symptoms of the disease. But for the improvement of secondary symptoms, the observation group was better than the control group, such as joint pain, swelling of the head and so on. Conclusion: after observation and contrast of curative effect, it was found that the therapeutic effect of Qingfei Hua Yin Zubi granule in relieving cough, expectoration, asthma and other symptoms was the same as that of hormone application in the treatment of severe stage of lung arthralgia (cold drink entrapped lung, lung collaterals obstruction), and other symptoms, such as cough, expectoration and shortness of breath, etc. But it is superior to hormone therapy in relieving joint pain and swelling of head and face of limbs, and has the advantages of convenient medication, less side effects, easy to carry, and so on. It has extensive application and popularization value.
【学位授予单位】:长春中医药大学
【学位级别】:硕士
【学位授予年份】:2016
【分类号】:R259
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