福州社区轻度认知障碍老年人群中医证素分布规律及其影响因素研究

发布时间：2018-05-10 12:29

本文选题：轻度认知障碍 + 老年人　；参考：《福建中医药大学》2017年硕士论文

【摘要】：目的:本文旨在探讨福州市轻度认知障碍(mild cognitive impairment,MCI)老年人中医证素分布规律及其与影响因素的关系,为MCI证素特征研究及中医药防治MCI提供理论依据。方法:采用横断面调查研究设计,收集福州市306名社区MCI老年人中医证候信息及影响因素情况,采用证素辨证法,计算证素频率和证素诊断轻重程度,利用描述性分析,卡方检验,秩和检验等方法综合分析MCI老年人中医证素与影响因素的相关性。结果:1.MCI老年人的中医证素特征:病位证素主要以肝(150,49.02%)、肾(148,48.37%)为主,其次为心(95,31.05%)、心神(脑)(62,20.26%)、胆(57,18.63%);主要虚性证素为阳虚(177,57.84%)、血虚(170,55.56%)、阴虚(164,53.59%)、气虚(156,50.98%);主要实性证素为:痰(103,33.66%)、气滞(100,32.68%)、湿(70,22.88%)、热(41,13.40%)。2.证素与性别的关系:女性肝、肾、心证素频率较男性高(P0.05);在心证素诊断轻重程度上,女性在轻度频率较男性为低,中度、重度频率为高(P0.05)。3.证素与年龄的关系:70岁及以上MCI老年人在阳虚、血虚、阴虚、气虚证素的频率高于60-69岁MCI老年人(P0.05);在阳虚证素诊断轻重程度上,60-69岁MCI老年人在轻度、中度频率分布较70岁以上MCI老年人高,重度频率为低(P0.05);在血虚证素诊断轻重程度上,60-69岁MCI老年人在轻度频率分布较70岁以上MCI老年人高,中度、重度频率分布为低(P0.05)。4.证素与吸烟的关系:无吸烟习惯的MCI老年人在血虚、气虚证素频率上较有吸烟习惯的MCI老年人高(P0.05)。5.证素与饮酒的关系:在肝证素诊断轻重程度上,有饮酒习惯的MCI老年人在轻度的频率分布较无饮酒习惯的MCI老年人为低,在中度、重度的频率分布为高(P0.05);在气虚证素诊断轻重程度上,有饮酒习惯的MCI老年人在轻度频率分布为高,在中度、重度频率分布为低(P0.05)。6.证素与家族痴呆病史的关系:不同家族痴呆病史的MCI老年人在中医证素频率与证素诊断轻重程度上差异均无统计学意义(P0.05)。7.证素与高血压病史的关系:有高血压病史的MCI老年人在阴虚证素诊断轻重程度分布上较无高血压病史的MCI老年人在轻度频率分布上为高,在中度、重度频率分布上为低(P0.05)。8.证素与有无规律运动的关系:有规律运动的MCI老年人肾、心、心神(脑)、阳虚、血虚、气虚证素频率较无规律运动的MCI老年人低(P0.05)。9.证素与职业劳动方式的关系:以脑力劳动为主的MCI老年人在阳虚证素频率上较以体力劳动为主的MCI老年人低(P0.05);在胆、气滞证素诊断轻重程度上,以体力劳动作为职业劳动方式为主的MCI老年人在中度和重度频率分布上较以脑力劳动作为职业劳动方式为主的MCI老年人为高,轻度频率分布为低(P0.05)。结论:1.MCI老年人病位证素主要在肝、肾、心、心神(脑)、胆;病性证素主要为阳虚、血虚、阴虚、气虚、痰、气滞、湿、热。2.MCI老年人证素特点在一定程度上与性别、年龄、吸烟情况、饮酒情况、高血压病史、有无规律运动及职业劳动方式有关。
[Abstract]:Objective: the purpose of this paper is to explore the distribution of TCM syndrome in mild cognitive impairment (MCI) and its relationship with the influencing factors in Fuzhou, and to provide a theoretical basis for the study of MCI characteristics and the prevention and control of traditional Chinese medicine (MCI). Methods: a cross-sectional study was designed to collect the traditional Chinese medicine of the 306 elderly people in the community of Fuzhou. Syndrome differentiation and syndrome differentiation method were used to calculate the degree of syndrome factor frequency and the degree of diagnosis of syndrome elements. The correlation between TCM syndrome factors of MCI aged people and influencing factors was analyzed by descriptive analysis, chi square test, rank test and other methods. Results: the characteristics of TCM syndrome in 1.MCI elderly were mainly liver (150,49.02 %), 148,48.37%, followed by 95,31.05%, 62,20.26%, and 57,18.63%; the main deficiency syndrome is Yang deficiency (177,57.84%), blood deficiency (170,55.56%), yin deficiency (164,53.59%), and Qi deficiency (156,50.98%); the main real syndrome is the relationship between phlegm (103,33.66%), Qi Stagnation (100,32.68%), wet (70,22.88%), heat (41,13.40%) and sex: The frequency of female liver, kidney and heart syndrome was higher than that of male (P0.05); in the degree of diagnosis of cardiac syndrome, women were lower than men in mild frequency, moderate and severe frequency was higher (P0.05).3. syndrome and age: the frequency of MCI aged 70 and above in Yang deficiency, blood deficiency, yin deficiency and Qi deficiency syndrome was higher than that of 60-69 years old MCI elderly (P0.05); in Yang Deficiency Syndrome The grade of MCI aged 60-69 years old was mild, the moderate frequency was higher than that of MCI older than 70 years old, and the severe frequency was low (P0.05). In the degree of diagnosis of blood deficiency syndrome, the mild frequency distribution of MCI aged 60-69 years was higher than that of MCI older people above 70 years old, and the moderate and severe frequency distribution was low (P0.05).4. syndrome and smoking. Department: the relationship between high (P0.05).5. (P0.05).5. syndrome and alcohol consumption of elderly people who have no smoking habit in the frequency of blood deficiency and Qi deficiency than that of smoking habits: in the degree of liver syndrome, the mild frequency distribution of MCI aged people with drinking habits is lower than that of MCI elderly people who have no drinking habits, and the moderate and severe frequency distribution is in the moderate and severe frequency. High (P0.05); in the severity of qi deficiency syndrome, the mild frequency distribution of MCI aged people with drinking habit was high, and the relationship between the moderate and severe frequency distribution was low (P0.05).6. syndrome and the family history of dementia: there was no statistical difference between the MCI elderly in the history of different family dementia and the degree of diagnosis of TCM syndrome. The relationship between the significance (P0.05).7. syndrome and the history of hypertension: the MCI elderly in the history of hypertension are higher in the severity of the diagnosis of yin deficiency syndrome than in the mild frequency distribution of the MCI elderly without the history of hypertension. The relationship between the moderate and severe frequency distribution is the relationship between the low (P0.05).8. syndrome and the irregular movement: the regular movement of MCI The relationship between the elderly people with kidney, heart, heart, heart (brain), Yang deficiency, blood deficiency and Qi deficiency syndrome is lower (P0.05).9. syndrome factor and occupational labor mode of MCI elderly people with no regular movement: the MCI elderly with mental labor are lower than those of MCI elderly with physical labor (P0.05) in the frequency of Yang deficiency syndrome, and the severity of the diagnosis of bile and qi stagnation is in the degree of severity. MCI elderly people with physical labor as the main mode of labor are higher in moderate and severe frequency than those of MCI with mental labor as the main working mode of labor, and the light frequency distribution is low (P0.05). Conclusion: the main symptoms of 1.MCI in the elderly are liver, kidney, heart, heart (brain) and gallbladder, and the main syndromes of the disease are Yang deficiency and blood deficiency, Yin deficiency, Qi deficiency, phlegm, qi stagnation, dampness, and heat.2.MCI are related to sex, age, smoking, drinking, history of hypertension, irregular movement and occupational labor.

【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.7

【参考文献】