梅花针治疗肝肾不足型斑秃的临床观察

发布时间：2018-05-11 01:09

本文选题：梅花针 + 肝肾不足型　；参考：《广西中医药大学》2016年硕士论文

【摘要】：目的:观察梅花针疗法针对肝肾不足型斑秃的临床疗效及安全性。探讨梅花针治疗肝肾不足型斑秃的作用机制。为进一步研究梅花针治疗肝肾不足型斑秃的现代作用机理及后期防治提供新的理论依据及方法,从而为临床提供一种较好的治疗方案。方法:依据患者的症状及体征,将89例受试者,采取随机、对照的临床研究方法,分为治疗组30例,对照组30例,空白组29例。其中治疗组给予梅花针扣刺治疗,治疗前用75%的医用酒精对皮损局部进行消毒,采取螺旋式由外向内扣刺,皮损局部采用中度扣刺手法,微出血为度,配穴处扣刺以轻度扣刺为主,局部出现红晕为度,每隔3日治疗一次,每周两次;对照组使用5%米诺地尔酊外涂,并进行局部按摩5-10分钟,每日两次;空白组以75%的医用酒精进行局部外涂,并进行局部按摩5-10分钟,每日两次,三组皆经治疗3个疗程后,对其进行疗效评价。通过斑秃症状治疗前后的评分,并记录治疗过程当中出现的不良反应。试验结束后,针对第3个月进行随访。采用SPSS17.0统计软件将获得的数据进行统计分析。结果:1.临床疗效:治疗组30例患者,临床治愈12例,显效11例,有效5例,无效2例,总有效率93.33%。30例对照组,临床治疗愈3例,显效7例,有效11例,无效9例,总有效率70.00%。空白组29例,临床治愈1例,显效2例,有效3例,无效23例,总有效率20.69%。经秩和检验分析可知,Z=36.210,P=0.0000.50,具有显著性差异。2.临床皮损总积分对比:治疗前,三组脱发区症状总积分差异无统计学意义(P0.05),三组具有可比性。治疗组治疗后脱发区症状积分减小,治疗前后比较(P0.05),有显著性差异,有统计学意义;对照组治疗后脱发区症状积分减小,治疗前后比较(P0.05),有显著性差异;空白组治疗后脱发区症状积分减小,治疗前后比较(P0.05),有显著性差异,三组治疗后脱发区症状积分均减小,治疗前后比较(P0.05),有显著性差异。3.起效时间比较:经治疗,治疗组和对照组、空白组起效时间比较(P0.05),有显著性差异。4.治疗后的第3个月随访,对治疗组患者再次进行脱发区症状评估,治疗后,第3个月随访,三组患者复发率比较(P0.05),有显著性差异。结论:梅花针在治疗肝肾不足型斑秃方面,其疗效确切,安全性好,起效较快,复发率低,未见明显副作用;其临床起效和疗效时间均优于5%米诺地尔酊。梅花针疗法的治疗机制目前尚未明确,依据梅花针的治病原理考虑可能是其作用于皮肤,使局部气血通畅,血液微循环扩张,血液循环速度加快,同时邪气由腠理而出,局部的异常因子恢复平衡,阴阳调和,局部毛发得到滋养、生长。本试验根据辨证论治进行取穴,从人体整体进行内部气机调整,促进局部头发的生长。此方法安全,效果显著,操作简易,值得在临床上推广使用。
[Abstract]:Objective: to observe the clinical efficacy and safety of plum blossom needle therapy in treating alopecia areata with deficiency of liver and kidney. To explore the mechanism of plum blossom needle in treating alopecia areata with deficiency of liver and kidney. In order to further study the modern mechanism of the treatment of alopecia areata with deficiency of liver and kidney, and provide a new theoretical basis and method for the prevention and treatment of alopecia areata in the later stage. Methods: according to the symptoms and signs of the patients, 89 subjects were randomly divided into treatment group (n = 30), control group (n = 30) and blank group (n = 29). Before treatment, 75% of medical alcohol was used to sterilize the local lesions. The skin lesions were treated with spiral puncture from the outside to the inside. The local lesions were treated with moderate buckling technique, and the degree of slight hemorrhage was slight. The main points were mild buckling and local redness, which was treated twice a week every 3 days, while the control group was treated with 5% minodil tincture and local massage for 5-10 minutes twice a day, while the control group was treated with 5% minodil tincture for 5 to 10 minutes, twice a day, while the control group was treated with 5% minodil tincture. The blank group was treated with 75% medical alcohol and local massage for 5-10 minutes, twice a day. The curative effect of the three groups was evaluated after three courses of treatment. Symptoms of alopecia areata were evaluated before and after treatment, and adverse reactions were recorded. At the end of the trial, follow-up was conducted for the third month. SPSS17.0 statistical software will be used to obtain the data for statistical analysis. The result is 1: 1. Clinical efficacy: in the treatment group, 12 cases were cured, 11 cases were markedly effective, 5 cases were effective, 2 cases were ineffective, the total effective rate was 93.33.30 cases in the control group, 3 cases were cured, 7 cases were markedly effective, 11 cases were effective, 9 cases were ineffective, and the total effective rate was 70.003%. There were 29 cases in blank group, 1 case was cured, 2 cases were effective, 3 cases were effective, 23 cases were ineffective, the total effective rate was 20.699. The results of rank sum test showed that the results of RSR were 0.0000.50, and there was significant difference between them (0.0000.50, P < 0.05, P < 0.05, P < 0.05, P < 0.05, P < 0.05). Comparison of the total score of clinical lesions: before treatment, there was no significant difference in the total score of symptoms in the alopecia area among the three groups (P 0.05), and the three groups were comparable. The symptom score of the alopecia area in the treatment group was decreased after treatment, and there was significant difference between the two groups before and after treatment, while in the control group, the symptom score of the alopecia area decreased after treatment, and there was significant difference between the two groups before and after treatment. The symptom score of alopecia area in the blank group was decreased after treatment, and there was significant difference between before and after treatment (P 0.05). The symptom score of hair loss area in the three groups decreased after treatment, and there was significant difference between before and after treatment (P 0.05). Effect time comparison: after treatment, treatment group and control group, blank group effect time compared with P0.05, there was significant difference. 4. After 3 months follow-up, the patients in the treatment group were evaluated for the symptoms of alopecia area again. After 3 months follow-up, the recurrence rate of the three groups was significantly higher than that of the control group (P 0.05). Conclusion: plum blossom needle is effective and safe in treating alopecia areata with deficiency of liver and kidney, and its clinical effect and curative time are better than 5% minoxidil tincture. The therapeutic mechanism of plum blossom needle therapy is not clear at present. According to the principle of plum blossom needle treatment, it may be considered that it acts on the skin, makes local qi and blood flow unobstructed, blood microcirculation dilates, blood circulation speeds up, and the evil gas comes out of striae at the same time. Local abnormal factors restore balance, Yin and Yang harmony, local hair nourishment, growth. According to differentiation of symptoms and signs, the experiment takes acupoints and adjusts the internal air engine from the whole human body to promote the growth of local hair. This method is safe, effective and easy to operate. It is worth popularizing in clinic.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.7

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