蛇六谷联合辨证施治对三阴性乳腺癌术后患者细胞免疫功能的影响

发布时间：2018-05-11 03:13

本文选题：蛇六谷 + 三阴性乳腺癌　；参考：《南京中医药大学》2017年硕士论文

【摘要】：目的:通过观察蛇六谷联合辨证论治对三阴性乳腺癌术后患者细胞免疫功能及临床中医症候群的影响,分析其临床疗效,为临床应用提供一定的科学依据。方法:2015年1月～2017年1月期间江苏省中医院名医堂及江苏省肿瘤医院乳腺科收治的三阴性乳腺癌患者,随机选取55例。此55例患者均为乳腺癌术后,均已行EC-T方案化疗8个周期,未行放疗,且病理诊断为三阴性乳腺癌。此55例患者采用自身前后对照的方法,其中先"单纯根据症状辨证选方"治疗3个月,此为第一个治疗周期;后改为"根据症状辨证选方联合蛇六谷"再治疗3个月,此为第二个治疗周期。所有患者治疗6个月后,通过对中医症状积分、体力健康状况的评分及细胞免疫指标变化的观察,比较两种治疗方法对三阴性乳腺癌术后患者细胞免疫功能及中医症候群等的影响。结果:"辨证选方联合蛇六谷"的治疗方法在改善细胞免疫功能方面优于"单纯辨证选方不联合蛇六谷"者,P0.05,两者有统计学意义。而在中医症候群、体力健康状况的改善方面,两者的差异无统计学意义(P0.05)。结论:用"蛇六谷联合辨证选方"治疗三阴性乳腺癌术后患者,与"单纯辨证选方"相比,可更好的改善患者的细胞免疫功能,蛇六谷的应用值得临床推广。
[Abstract]:Objective: to observe the effect of Snake Liugu combined with syndrome differentiation on cellular immune function and clinical TCM syndrome in patients with triple-negative breast cancer, and to provide scientific basis for clinical application. Methods: from January 2015 to January 2017, 55 patients with triple negative breast cancer were randomly selected from Mingyitang of Jiangsu Provincial traditional Chinese Medicine Hospital and Department of Breast of Jiangsu Cancer Hospital. All of the 55 patients had been treated with EC-T regimen for 8 cycles without radiotherapy, and the pathological diagnosis was triple negative breast cancer. The 55 patients were treated with the method of self-control before and after treatment, in which the first treatment period was "simply according to syndrome differentiation prescription" for 3 months, and then changed to "according to syndrome differentiation prescription combined with snake six grain" for another 3 months. This is the second treatment cycle. After 6 months of treatment, all the patients were observed on the scores of TCM symptoms, physical health and cellular immunity. To compare the effects of two treatment methods on cellular immune function and TCM syndrome in patients with triple-negative breast cancer after operation. Results: the therapeutic method of "syndrome differentiation and selecting prescription combined with snake six grain" was better than that of "simple syndrome differentiation prescription not combined with snake six grain" in improving the cellular immune function. There was statistical significance between the two methods. However, there was no significant difference in the improvement of physical health in TCM syndrome group (P 0.05). Conclusion: the treatment of triple negative breast cancer with "snake six grain combined with syndrome differentiation and selecting prescription" can improve the cellular immune function of patients better than that of "simple differentiation and selection of symptoms", and the application of snake six grain is worth popularizing in clinic.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R273

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