参松养心胶囊治疗稳定型心绞痛疗效及对hs-CRP及IL-6的影响

发布时间：2018-05-11 20:03

本文选题：稳定型心绞痛 + 参松养心胶囊　；参考：《广东医学》2017年S1期

【摘要】：目的检测参松养心胶囊用于稳定型心绞痛的临床疗效及对血清中超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)水平变化的影响。方法选取心内科就诊患者80例,随机分为观察组及对照组,每组各40例。对照组常规给予阿司匹林肠溶片、琥珀酸美托洛尔缓释片、硝酸酯类、他汀类及血管紧张素转化酶抑制剂(ACEI)类药物;观察组在对照组的基础上加用参松养心胶囊,8周为一疗程。比较两组治疗前后心绞痛临床疗效及血清hs-CRP、IL-6水平变化。结果 (1)两组患者心绞痛症状及心电图改善显效率差异有统计学意义(P0.05),总有效率差异无统计学意义(P0.05);两组的不良反应率极低,差异无统计学意义(P0.05)。(2)观察组及对照组血清hs-CRP、IL-6治疗前后差异均有统计学意义,治疗后观察组比对照组下降更多,且差异有统计学意义(P0.05)。结论 (1)参松养心胶囊能改善稳定型心绞痛症状及心电图。(2)参松养心胶囊和常规治疗均能降低稳定型心绞痛患者hs-CRP及IL-6的水平,参松养心胶囊效果更明显。因此,参松养心胶囊对稳定型心绞痛患者有较好的治疗作用,可以临床推广应用。
[Abstract]:Objective to detect the clinical effect of Shensong Yangxin capsule on stable angina pectoris and its effect on the level of serum hypersensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6). Methods 80 patients with cardiology were randomly divided into observation group and control group with 40 cases in each group. The control group was routinely given aspirin enteric-coated tablets, metoprolol succinate sustained release tablets, nitrate esters, statins and angiotensin converting enzyme inhibitor ACEI, and the observation group was treated with Shensong Yangxin capsule for 8 weeks on the basis of the control group. To compare the effect of angina pectoris and the level of serum hs-CRP-6-6 before and after treatment between the two groups. Results (1) there was significant difference in the significant improvement rate of angina pectoris and electrocardiogram between the two groups (P 0.05), but there was no significant difference in the total effective rate (P 0.05), and the adverse reaction rate was very low in the two groups. There was no significant difference between the observation group and the control group before and after treatment. After treatment, the serum hs-CRPnIL-6 in the observation group decreased more than that in the control group, and the difference was statistically significant (P 0.05). Conclusion 1) Shensong Yangxin capsule can improve the symptoms of stable angina pectoris and ECG. 2) Shensong Yangxin capsule and routine treatment can both reduce the levels of hs-CRP and IL-6 in patients with stable angina pectoris, and the effect of Shensong Yangxin capsule is more obvious. Therefore, Shensong Yangxin capsule has good therapeutic effect on stable angina pectoris and can be popularized in clinic.
【作者单位】：淄博万杰肿瘤医院内科;
【分类号】：R259

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