西黄胶囊治疗轻、中度癌性疼痛临床研究

发布时间：2018-05-14 19:57

本文选题：癌性疼痛 + 西黄胶囊　；参考：《河南中医》2017年05期

【摘要】：目的:观察西黄胶囊治疗轻中度癌性疼痛的临床疗效。方法:将60例轻度癌痛患者随机分为治疗组和对照组,每组各30例,对照组给予塞来昔布胶囊,治疗组给予西黄胶囊。将64例中度癌痛患者随机分为治疗组和对照组,每组各32例。对照组给予盐酸曲马多缓释胶囊,治疗组在对照组的基础上给予西黄胶囊。观察各组的临床疗效,生活质量疗效、止痛起效时间及维持时间。结果:轻度癌痛患者治疗组效率为83.3%,对照组有效率为86.7%,两组有效率比较,差异无统计学意义(P0.05);治疗组止痛起效时间为(4.26±0.81)h,对照组为(1.43±0.67)h,差异具有统计学意义(P0.01),但两组止痛维持时间比较,差异无统计学意义(P0.05);两组生活质量疗效比较,差异无统计学意义(P0.05)。中度癌痛治疗组有效率为84.4%,对照组有效率为65.6%,两组患者临床疗效比较,差异具有统计学意义(P0.05);治疗组止痛起效时间(39.11±9.65)min,短于对照组的(45.36±9.44)min,两组比较,差异具有统计学意义(P0.05);治疗组止痛维持时间为(10.52±1.58)h,长于对照组的(9.56±1.55)h,差异具有统计学意义(P0.05);两组生活质量疗效比较,差异具有统计学意义(P0.05)。结论:西黄胶囊可单独运用于轻度癌性疼痛,起效时间稍长;对于中度疼痛,西黄胶囊联合西药止痛剂可以提高止痛疗效,缩短起效时间,延长止痛维持时间,且可提高患者生活质量。
[Abstract]:Objective: to observe the clinical effect of Xihuang capsule on mild and moderate cancer pain. Methods: 60 patients with mild cancer pain were randomly divided into treatment group (n = 30) and control group (n = 30). The control group was given celecoxib capsule and the treatment group was treated with Xihuang capsule. 64 patients with moderate cancer pain were randomly divided into treatment group and control group with 32 cases in each group. The control group was given tramadol hydrochloride sustained release capsule, and the treatment group was given Xihuang capsule on the basis of control group. The clinical effect, quality of life, analgesic effect and maintenance time were observed. Results: the effective rate was 83.3 in the treatment group and 86.7 in the control group. There was no significant difference between the two groups (P 0.05), the time of analgesic effect in the treatment group was 4.26 卤0.81hand that in the control group was 1.43 卤0.67h. the difference was statistically significant, but there was no significant difference between the two groups in the maintenance time of pain relief (P 0.05), there was no significant difference in the effect of quality of life between the two groups (P 0.05). The effective rate of moderate cancer pain treatment group was 84.4 and that of control group was 65.65.The difference between the two groups was statistically significant (P 0.05), the time of analgesic effect in treatment group was 39.11 卤9.65 min, shorter than that in control group (45.36 卤9.44 min). The difference was statistically significant (P 0.05), the maintenance time of pain relief in the treatment group was 10.52 卤1.58 h, which was longer than that in the control group (9.56 卤1.55 h), the difference was statistically significant (P 0.05), and the difference was statistically significant compared with the control group (P 0.05). Conclusion: Xihuang capsule can be used for mild cancer pain alone, and for moderate pain, Xihuang capsule combined with western medicine analgesic can improve the analgesic effect, shorten the onset time and prolong the maintenance time of pain relief. And can improve the quality of life of patients.
【作者单位】：湖南中医药大学;湖南省中医药研究院附属医院;
【分类号】：R273

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