紫及生肌膏促进肛瘘术后创面愈合的临床疗效观察

发布时间：2018-05-19 00:18

本文选题：紫及生肌膏 + 肛瘘术后　；参考：《福建中医药大学》2016年硕士论文

【摘要】：目的：对比紫及生肌膏纱条换药与凡士林纱条换药对肛瘘术后第10天辨证为虚证创面愈合的影响,主要通过观察创面疼痛情况、创面分泌物情况、创面肉芽组织生长、创面面积等,探讨紫及生肌膏纱条换药对低位单纯性肛瘘术后创面愈合影响的临床疗效。方法：将纳入本实验的研究对象60例患者,随机分为治疗组30例及对照组30例。治疗组术后第2天予凡士林纱条换药,术后第10天改予紫及生肌膏纱条换药,对照组则单纯予凡士林纱条换药。受试者用药前的一般情况(如性别、年龄、病程等)以及个体的局部症状及体征(如创面分泌物、疼痛情况、肉芽生长情况等)进行统计学比较,然后详细记录比较两组在术后第13天(用药后第3天)、术后第18天(用药后8天)、术后第25天(用药后第15天)创面分泌物、疼痛、肉芽组织的积分情况,计算术后第18天、术后第25天创面面积,术后第28天评价治疗后总体疗效。按照各评价指标,客观记录各评价得分,数据均采用统计学软件SPSS18.0进行统计对比,得出统计结果,最终得出试验结论。结果：本试验共60例纳入对象,完成60例,其中治疗组、对照组各30例。实验结果如下：(1)创面疼痛：两组受试者在术后第13、18、25天创面疼痛进行统计学比较,差异‘有统计学意义(P0.05),说明治疗组在用药后第3天起改善疼痛情况明显优于对照组。(2)创面分泌物：两组受试者在术后第13、18、25天创面分泌物分别比较,两组差异有统计学意义(P0.05),说明治疗组在用药后第3天起改善分泌物情况明显优于对照组。(3)创面肉芽生长：两组在术后第18、25天创面肉芽生长分布分别比较,两组差异有统计学意义(P0.05),说明治疗组在用药后第8天起改善肉芽生长情况明显优于对照组。(4)创面面积：两组术后第18、25天与用药前进行组内比较,均P0.05,差异均具有统计学意义,表明两组在用药后第8天起均有缩小创面面积的作用；两组术后第18、25天进行组间比较,均P0.05,差异均具有统计学意义,说明治疗组在缩小创面面积方面明显优于对照组。(5)创面愈合时间：两组受试者创面愈合时间经统计学比较,均P0.05,差异具有统计学意义,表明治疗组在促进创面愈合方面明显优于对照组。(6)总疗效：两组术后第28天总疗效比较,对照组创面治愈率为83.33%,治疗组为100%,两组创面28天总疗效比较,经统计分析(P0.05),差异有统计学意义,说明治疗组在促进创面愈合方面明显优于对照组。(7)不良反应：两组试验过程中无不良反应情况出现。结论：经过分析本课题研究结果,可认为肛瘘术后紫及生肌膏纱条换药组的疗效优于凡士林纱条换药组,主要体现在减少并改善创面分泌物、减轻创面疼痛情况、促进创面肉芽生长及创面愈合等方面。
[Abstract]:Objective: to compare the effect of dressing change between purple and Shengji ointment and vaseline gauze on wound healing of deficiency syndrome after 10 days of anal fistula, mainly by observing the condition of wound pain, the condition of wound secretion and the growth of wound granulation tissue. To investigate the effect of dressing change of purple and Shengji ointment on wound healing after low simple anal fistula. Methods: 60 patients were randomly divided into treatment group (n = 30) and control group (n = 30). In the treatment group, vaseline gauze was changed on the second day after operation, purple and Shengji ointment gauze was changed on the 10th day after operation, and the control group was treated with vaseline gauze only. The general conditions (such as sex, age, course of disease, etc.) and local symptoms and signs (such as wound discharge, pain, granulation growth, etc.) were compared statistically. Then the scores of wound secretion, pain and granulation tissue were recorded and compared in the two groups on the 13th day (3 days after medication), 18 days (8 days after medication), 25 days (15 days after medication), and 18 days after operation. The wound area was evaluated on the 25th day after operation and the overall curative effect was evaluated on the 28th day after operation. According to each evaluation index, objective record each evaluation score, the data all use the statistics software SPSS18.0 to carry on the statistical contrast, obtains the statistical result, finally obtains the test conclusion. Results: 60 cases were included in the experiment, including 30 cases in the treatment group and 30 cases in the control group. The results of the experiment were as follows: (1) wound pain: the two groups were statistically compared with each other on the 13th day, 1825 days after operation, The difference was statistically significant (P 0.05), which indicated that the treatment group was superior to the control group in improving the pain state from the 3rd day after treatment: the wound secretion of the two groups was compared on the 13th day, 1825 days after operation, respectively. The difference between the two groups was statistically significant (P 0.05), which indicated that the improvement of secretion in the treatment group was significantly better than that in the control group from the third day after treatment: the distribution of granulation growth in the two groups was compared on the 1825 day after operation. The difference between the two groups was statistically significant (P 0.05), which indicated that the improvement of granulation growth in the treatment group was significantly better than that in the control group from the 8th day after treatment. The wound area of the treatment group was significantly better than that of the control group (P 0.05). The results showed that the two groups had the effect of reducing the wound area from the 8th day after treatment, and the difference was statistically significant between the two groups on the 25th day after operation (P0.05). The results showed that the healing time of the treatment group was significantly better than that of the control group in reducing the wound area. The wound healing time of the two groups was significantly higher than that of the control group (P 0.05). The results showed that the treatment group was obviously superior to the control group in promoting wound healing: the total curative effect of the two groups on the 28th day after operation was 83.33 in the control group, 100 in the treatment group, and 28 days in the two groups. The difference was statistically significant, which indicated that the treatment group was superior to the control group in promoting wound healing. Conclusion: by analyzing the results of this study, we can conclude that the curative effect of purple and Shengji ointment dressing changing group after anal fistula is better than that of vaseline gauze exchange group, which is mainly reflected in the reduction and improvement of wound secretion and the relief of wound pain. Promote the growth of granulation and wound healing.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266

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