养血柔肝法治疗肝郁血虚型视神经萎缩的临床研究

发布时间：2018-05-21 11:40

本文选题：视神经萎缩 + 肝与目的关系　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:针对视神经萎缩的病证特点,以中医理论为指导,确立养血柔肝的治疗方法。通过对治疗前后肝郁血虚型视神经萎缩患者的视力、视野、神经纤维层厚度的观察,评价其临床疗效,为中医治疗视神经萎缩提供新的方法和思路。方法:将符合入选标准的40例视神经萎缩患者,随机分成两组。其中,治疗组20例27只眼,口服养血柔肝明目汤配合针刺;对照组20例25只眼,采用针刺治疗。两组都配合口服甲钴胺分散片、穴位贴服。将两组患者治疗前后中医症候积分、视力、视野(MD、PSD)以及RNFL厚度进行比较,评价其临床疗效。结果:治疗组中医症候总有效率为96.7%,对照组中医症候总有效率为90.4%,两组疗效比较差异有统计学意义(P0.05)。治疗组视力总有效率为85.2%,对照组视力总有效率为60%,两组疗效比较差异有统计学意义。治疗组在视野、RNFL厚度等方面与对照组比较差异均有统计学意义(P0.05)。结论:养血柔肝法治疗肝郁血虚型视神经萎缩疗效明显,能显著提高患者视觉功能,改善症状,具有良好的临床应用价值。
[Abstract]:Objective: to establish the treatment of nourishing blood and softening liver under the guidance of traditional Chinese medicine (TCM) according to the characteristics of optic nerve atrophy. By observing the visual acuity, visual field and the thickness of nerve fiber layer in patients with optic nerve atrophy of liver stagnation and blood deficiency before and after treatment, the clinical effect was evaluated, and a new method and thought for the treatment of optic nerve atrophy by traditional Chinese medicine was provided. Methods: 40 patients with optic nerve atrophy were randomly divided into two groups. Among them, 20 cases (27 eyes) in the treatment group were treated by acupuncture combined with Yangxue Rugan Mingmu decoction and 25 eyes in the control group. Both groups were combined with oral methylcobalamin dispersible tablets, acupoint application. The scores of TCM symptoms, visual acuity, visual field and RNFL thickness before and after treatment were compared between the two groups, and the clinical efficacy was evaluated. Results: the total effective rate of TCM symptoms in the treatment group was 96.7m, while that in the control group was 90.4. The difference between the two groups was statistically significant (P 0.05). The total effective rate of visual acuity was 85.2 in the treatment group and 60 in the control group. The RNFL thickness in the treatment group was significantly different from that in the control group (P 0.05). Conclusion: the method of nourishing blood and softening liver is effective in the treatment of optic nerve atrophy with liver stagnation and blood deficiency. It can significantly improve the visual function and symptoms of the patients and has a good clinical application value.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R276.7

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