祛瘀通经方治疗前列腺炎不育症患者症状评分及对血清瘦素与精浆生化指标的影响

发布时间：2018-05-21 17:21

本文选题：祛瘀通经方 + 前列腺炎　；参考：《时珍国医国药》2017年08期

【摘要】：目的探究祛瘀通经方对前列腺炎不育症患者症状评分、血清瘦素与精浆生化指标的影响。方法随机数字表法将232例慢性前列腺炎不育症患者分成研究组和对照组各116例。两组患者均予以常规西药治疗(左氧氟沙星+锌硒宝片);研究组在上述基础上加用自拟中药方祛瘀通经方。比较其治疗前后症状评分[慢性前列腺炎症状评分量表(NIHCPSI)]评估结果及血清瘦素(Lep)、精浆生化指标(果糖、精浆弹性硬蛋白酶)、精子质量[精子(a+b)级活动力、精子畸形率、精子密度、精子成活率]检测结果,记录两组患者配偶治疗后1年内成功妊娠率。结果治疗12周后,两组NIHCPSI评估结果、血清Lep水平、精浆弹性硬蛋白酶检测结果及精子畸形率均较治疗前显著降低,且研究组对照组(P均0.05);精浆果糖及部分精子质量指标[精子(a+b)级活动力、精子密度、精子成活率〗检测结果则较治疗前显著升高,且研究组对照组,差异均有统计学意义(P均0.05)。治疗后1年内,研究组患者配偶成功妊娠率为41.82%(46/110),明显高于对照组的28.04%(30/107),差异有统计学意义(P0.05)。结论祛瘀通经方联合常规西药治疗能有效促进慢性前列腺炎不育症患者病情转归,于其预后恢复有利。
[Abstract]:Objective to investigate the effects of Quyu Tongjing recipe on symptom score, serum leptin and seminal plasma biochemical index in patients with prostatitis infertility. Methods 232 patients with chronic prostatitis infertility were randomly divided into study group and control group. The two groups were treated with routine western medicine (levofloxacin zincselenite tablet) and the study group was treated with traditional Chinese medicine prescription Quyu Tongjing prescription on the basis of above mentioned. To compare the evaluation results of symptom score [chronic prostatitis symptom scale] before and after treatment, serum leptin, seminal plasma biochemical indexes (fructose, seminal plasma elastoprotease), sperm quality (sperm motility), sperm deformity rate. The results of sperm density and sperm survival rate were used to record the successful pregnancy rate within 1 year after treatment. Results after 12 weeks of treatment, the results of NIHCPSI evaluation, serum Lep level, seminal plasma elastase test and sperm abnormality rate in both groups were significantly lower than those before treatment. The results of seminal plasma fructose and some sperm quality indexes (sperm motility, sperm density, sperm survival rate) in the study group were significantly higher than those before treatment, and those in the study group were significantly higher than those in the control group. The difference was statistically significant (P < 0.05). Within one year after treatment, the successful pregnancy rate of spouses in the study group was 41.82% and 46.1 / 110%, which was significantly higher than that in the control group (28.04 / 30 / 107), and the difference was statistically significant (P 0.05). Conclusion Quyu Tongjing prescription combined with routine western medicine can effectively promote the prognosis of patients with chronic prostatitis infertility.
【作者单位】：河北省中医院;石家庄市第一医院;河北医科大学研究生学院;
【基金】：河北省中医药管理局科研计划项目(No.2016031)
【分类号】：R277.5

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