健脾化痰祛湿法治疗高尿酸血症合并糖耐量减低的临床疗效观察

发布时间：2018-05-24 00:14

本文选题：高尿酸血症 + 糖耐量减低　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:观察以健脾化痰祛湿法为治则组成的化痰祛湿方对高尿酸血症合并糖耐量减低的临床疗效并进行初步评价。方法:采用随机、平行对照的临床试验研究方法,将符合研究要求高尿酸血症合并糖耐量减低患者60例随机分为治疗组(30例)和对照组(30例),两组均采用常规高尿酸血症基础治疗,治疗组加用化痰祛湿方,对照组加用溴苯马隆,观察治疗前后的实验室检查指标、体征和临床症状的变化。结果:1.治疗组综合疗效总有效率为87.2%,对照组为73.9%,两组之间比较有差异性(P0.05)。2.治疗组中医症状改善总有效率为87.96%,对照组为72.57%,两组之间比较有差异性(P0.05)。3.化痰祛湿方在降低血尿酸、尿尿酸、血糖等方面均表现出较好的治疗效果,治疗前后可见显著差异(P0.05),但组间比较(P0.05)无差异性。4.化痰祛湿方在缓解疼痛、改善血脂、降低血糖方面均表现出较好的治疗效果,组间比较有差异性(P0.05)。结论:化痰祛湿方对高尿酸血症合并糖耐量减低患者血脂、2h血糖、血尿酸、尿尿酸、糖基化血红蛋白有明显改善作用,并可明显改善高尿酸血症合并糖耐量减低患者中医临床症状,提高生活质量,验证了采用化痰祛湿方治疗高尿酸血症合并糖耐量减低的可行性,为中医药防治高尿酸血症合并糖耐量减低提供了一种的新的思路与方法。
[Abstract]:Objective: To observe the clinical effect and preliminary evaluation of the prescription of "invigorating the spleen and eliminating phlegm and removing dampness" as a cure for hyperuricemia with impaired glucose tolerance. Methods: a randomized, parallel controlled clinical trial was used to divide 60 patients with hyperuricemia and impaired glucose tolerance into a treatment group (30 And the control group (30 cases), the two groups were treated with routine hyperuricemia, the treatment group was added with the recipe for eliminating phlegm and dampness, and the control group was added with bromate Malone. The laboratory examination indexes, signs and clinical symptoms were observed before and after the treatment. Results: the total effective effective rate of the 1. treatment group was 87.2%, the control group was 73.9%, and the two groups were worse than the other groups. The total effective rate of TCM symptom improvement in P0.05.2. treatment group was 87.96%, and the control group was 72.57%. The difference between the two groups was different (P0.05).3. phlegm and dampness and dampness prescription in reducing blood uric acid, urinic acid, blood sugar and so on, showed good therapeutic effect. There was significant difference before and after treatment (P0.05), but there was no difference of.4. phlegm between groups (P0.05). The prescription of dispelling dampness, improving blood lipid and lowering blood sugar showed good therapeutic effect, and there was a difference between the groups (P0.05). Conclusion: the prescription of eliminating phlegm and removing dampness has obvious improvement on hyperuricemia, 2h blood sugar, uric acid, uricuric acid and glycosylated hemoglobin, and it can obviously improve the high uric acid blood. The clinical symptoms and quality of life of patients with impaired glucose tolerance were improved, and the feasibility of treating hyperuricemia with impaired glucose tolerance was verified by using the prescription of eliminating phlegm and removing dampness. It provided a new idea and method for the prevention and control of hyperuricemia with impaired glucose tolerance in traditional Chinese medicine.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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