丹参注射液穴位注射配合走罐治疗寻常型痤疮的临床研究

发布时间：2018-05-24 06:46

  本文选题：寻常型痤疮 + 穴位注射　； 参考：《广西中医药大学》2016年硕士论文

【摘要】：目的：本研究通过对丹参注射液穴位注射配合走罐与口服异维A酸软胶囊(泰尔丝)联合外涂0.025%维A酸乳膏两者治疗寻常型痤疮的临床疗效进行对比,科学客观地评价丹参注射液穴位注射配合走罐治疗寻常型痤疮的临床疗效及安全性,为其在临床实践中的推广而提供较为客观的依据。方法：将符合本课题纳入标准的60例寻常型痤疮患者,随机地分成两组,治疗组收集30例,采用丹参注射液穴位注射配合走罐治疗,每3天进行丹参注射液穴位注射配合走罐1次,7次为1个疗程；药物对照组收集30例,口服异维A酸软胶囊(泰尔丝),每次10mg,1次/天,晚上外涂0.025%维A酸乳膏,3周为1个疗程。治疗两个疗程后进行治疗前后皮损总数目、皮损分级对比,观察两组临床疗效。结果：通过分析临床研究及统计学数据：临床疗效方面,治疗组共30例,痊愈20例,显效6例,有效3例,无效1例,总有效率为86.67%；药物对照组共30例,痊愈12例,显效7例,有效6例,无效6例,总有效率为63.33%,经检验P0.05,治疗组优于药物对照组,差异有统计学的意义；经过治疗后患者皮损数目两组间的差异有统计学意义P0.05；两组治疗组未痊愈患者皮损严重程度的分级：Ⅰ级的患者有5例,Ⅱ级的患者有4例,Ⅲ级的患者有1例；而对照组的患者中：Ⅰ级的患者有7例,Ⅱ级的患者有7例,Ⅲ级的患者有4例,经检验P0.05,差异具有统计学意义。治疗一个月后,临床疗效方面,30例治疗组患者痊愈有5例,显效16例,有效5例,无效4例,总体的有效率为70.00%；30例对照组患者中痊愈2例,显效8例,有效10例,无效10例,总体的有效率为33.33%,经检验P0.05,差异具有统计学意义；比较两组患者疗程结束后随访的复发率,治疗组的20例痊愈患者中有1例复发患者,复发率为5.00%;对照组中的12例痊愈患者有2例复发,复发率为16.67%；说明了丹参注射液穴位注射配合走罐的治疗方法远期的疗效也令人满意。结论：(1)丹参注射液穴位注射配合走罐疗法治疗寻常型痤疮除了有较好的近期疗效之外,还有着令人较为满意的远期疗效。(2)丹参注射液穴位注射配合走罐疗法能够清肺解毒,凉血活血,调理冲任,不仅改善患者的颜面部皮肤,还从整体上调节患者血液循环,提高患者机体的免疫能力,其综合疗效明显优于异维A酸软胶囊(泰尔丝)联合0.025%维A酸乳膏的治疗。(3)治疗组在治疗过程中没有出现明显的不良反应,药物对照组部分患者有口唇干裂、皮肤灼热、红斑、脱屑等不良反应,说明丹参注射液穴位注射配合走罐疗法比较常规西药治疗寻常型痤疮更加安全可靠。
[Abstract]:Objective: to compare the clinical efficacy of salvia miltiorrhiza injection combined with walking cupping and oral isotinic acid soft capsule (Tilsi) combined with 0.025% retinoic acid cream in the treatment of acne vulgaris. To evaluate scientifically and objectively the clinical efficacy and safety of salvia miltiorrhiza injection combined with cupping in the treatment of acne vulgaris, and to provide a more objective basis for its popularization in clinical practice. Methods: sixty patients with acne vulgaris were randomly divided into two groups. 30 patients in the treatment group were treated with acupoint injection of Salvia miltiorrhiza and cupping. Every 3 days, salvia miltiorrhiza injection acupoint injection combined with cupping for 7 times was used as a course of treatment, and 30 patients in the control group were treated with isotinic acid soft capsules (10 mg / day, 10 mg / day), and 0.025% retinoic acid cream was applied outside for 3 weeks as a course of treatment in the drug control group. After two courses of treatment, the total number of skin lesions and the grading of lesions were compared before and after treatment, and the clinical efficacy of the two groups was observed. Results: through the analysis of clinical research and statistical data: there were 30 cases in the treatment group, 20 cases were cured, 6 cases were effective, 3 cases were effective, 1 case was ineffective, the total effective rate was 86.67%, 30 cases were in the drug control group, 12 cases were cured, 7 cases were remarkable effect. There were 6 cases of effective and 6 cases of ineffective, the total effective rate was 63.33. The treatment group was better than the drug control group after testing (P0.05), the difference was statistically significant. After treatment, there was a significant difference in the number of skin lesions between the two groups (P 0.05). There were 5 cases of grade 鈪，

本文编号：1928089