参附注射液对老年骨折患者甲状腺素水平的影响及对心脏的保护作用

发布时间：2018-05-26 06:45

本文选题：参附注射液 + 骨折　；参考：《检验医学与临床》2017年09期

【摘要】：目的探讨参附注射液对老年骨折患者甲状腺素水平的影响及对心脏的保护作用。方法选取2014年7月至2015年6月该院收治的150例老年骨折患者作为研究对象,根据随机数字法分为观察组和对照组,每组75例。对照组采取相应的骨科处理,观察组在此基础上加以50mL的参附注射液进行治疗。观察两组患者心肌缺血、心律失常、室性早搏、室上性早搏发生情况,比较两组患者治疗前和治疗甲状腺素水平[三碘甲状腺原氨酸(T3)、甲状腺素(T4)、促甲状腺激素(TSH)]。结果治疗后,观察组的T3、T4、TSH甲状腺素水平显著高于对照组[(0.97±0.14)vs.(0.72±0.09)μg/L,(87.43±6.11)vs.(82.14±4.54)μg/L,(3.98±0.41)vs.(3.58±0.37)μg/L],差异有统计学意义(P0.05)。观察组的心肌缺血、室性早搏、室上性早搏、短阵室上性心动过速的发生率显著低于对照组[13.33%(10/75)vs.29.33%(22/75),9.33%(7/75)vs.21.33%(16/75),12.00%(9/75)vs.25.33%(19/75),8.00%(6/75)vs.20.00%(15/75)],差异有统计学意义(P0.05)。观察组的室性早搏为100~300次或大于300次,室上性早搏为100~300次或大于300次的发生率均比对照组低[4.00%(3/75)vs.18.67%(14/75),5.33%(4/75)vs.22.67%(17/75),2.67%(2/75)vs.17.33%(13/75),4.00%(3/75)vs.20.00%(15/75)],差异有统计学意义(P0.05)。结论老年骨折患者使用参附注射液能有效改善甲状腺素水平,降低心脑血管不良事件的发生率,对心脏具有保护性作用。
[Abstract]:Objective to investigate the effect of Shenfu injection on thyroxine level and heart protection in elderly patients with fracture. Methods from July 2014 to June 2015, 150 patients with senile fracture were selected and divided into observation group (n = 75) and control group (n = 75). The control group was treated with orthopaedics, and the observation group was treated with Shenfu injection of 50mL. Myocardial ischemia, arrhythmia, ventricular premature beats and supraventricular premature beats were observed in two groups. Results after treatment, the level of T3T4TSH in the observation group was significantly higher than that in the control group [0.97 卤0.14)vs.(0.72 卤0.09) 渭 g / L, 87.43 卤6.11)vs.(82.14 卤4.54 渭 g / L, 3.98 卤0.41)vs.(3.58 卤0.37 渭 g / L]. The difference was statistically significant (P 0.05). The incidence of myocardial ischemia, ventricular premature beats, supraventricular tachycardia in the observation group was significantly lower than that in the control group [13.33 / 10 / 75 vs.29.33 + 22 / 75 / 75 / 75 / 75 / 7 / 75 / 7.75 / 7.75 / 21.3375 / 12.00 12.00 / 9 / 75 vs.25.3319 / 75 / 8.00 / 6.75 / vs.20.00 / 15 / 75], there was a significant difference between the two groups (P 0.055.75). In the observation group, the incidence of 300 or more ventricular premature beats and 100 or more extrasystole beats in the observation group was lower than that in the control group [4.00 / 375 / v s.18.6775 / 1475 / 5.33], and there was a significant difference between the two groups (P < 0.05). Conclusion Shenfu injection can effectively improve the level of thyroxine, reduce the incidence of adverse cardiovascular and cerebrovascular events, and have protective effect on the heart.
【作者单位】：上海中医药大学附属曙光医院骨科;
【分类号】：R274.1

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