中风病（急性期）肝风内动证病因病机研究与临床调研

发布时间：2018-05-28 11:24

本文选题：中风病 + 急性期　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:探讨中风病急性期肝风内动证的病机理论内涵,以深化中风病防治研究思路。方法:通过梳理古今文献,明晰肝风内动致中病机理论的源流、发展和临床应用现状,明确肝风的本质、病因病机及其致病特点;采集中风病急性期患者的临床资料,运用统计学方法,找出相关的危险因素、症状体征,并对中风病肝风内动证患者发病14天内证候变化进行统计,分析证候演化规律,以探讨肝风致中的发病机理和病机特性。结果:性格急躁、情志刺激、既往高血压病史等与中风病急性期肝风内动证的发生存在相关性,起病急骤、病情数变、肌肉颤动、目偏不瞬、脉弦等为特征性临床表现。中风病肝风内动证组在发病后14天内,肝风内动证的出现频率不断降低,其证候分布情况有非常显著的差异(P0.01)。火热证、血瘀证在发病后明显增加,阴虚阳亢证和痰证出现频率始终高居不下。结论:肝风是中风病急性期起病和病程进展中的关键病理因素,中风病肝风内动证是急性期的重要证候。肝风上扰,痰瘀入络是肝风内动致中的发病机理。肝风善行数变,推动急性期的病机演化,是中风病病机级联反应的开端,与火热、痰、瘀、阴虚等中风病的常见病理因素的生成和致病密切相关。
[Abstract]:Objective: to explore the pathogenesis of acute stage of apoplexy in order to deepen the thinking of prevention and treatment of apoplexy. Methods: through combing the literature of ancient and modern times, the origin, development and clinical application of the theory of the pathogenesis of liver wind were clarified, the essence, etiology and pathogenesis of liver wind and its pathogenic characteristics were clarified, and the clinical data of patients with acute stroke were collected. Using statistical method to find out the related risk factors, symptoms and signs, and to statistics the changes of syndrome in 14 days after onset of apoplexy liver wind movement syndrome, and analyze the law of syndrome evolution, in order to explore the pathogenesis and pathogenesis of liver wind. Results: there was a correlation between personality irritability, emotional stimulation, history of past hypertension and the occurrence of liver wind-moving syndrome in acute stage of apoplexy, such as acute onset, number of illness, muscle fibrillation, uninstantaneous eye, pulse string and so on. Within 14 days after the onset of apoplexy, the frequency of liver wind motility syndrome in the apoplexy group decreased continuously, and the distribution of the syndromes was significantly different (P0.01). Heat syndrome, blood stasis syndrome increased significantly after the onset, Yin deficiency and hyperactivity of yang syndrome and phlegm syndrome has always been high frequency. Conclusion: liver wind is the key pathological factor in the onset and progression of stroke, and the syndrome of intrahepatic movement of apoplexy is an important syndromes in acute stage. Liver wind disturbance, phlegm stasis into the collaterals is the pathogenesis of liver wind. It is the beginning of cascade reaction of pathogenesis of apoplexy, which is closely related to the formation and pathogenesis of common pathological factors of apoplexy such as fire heat, phlegm, blood stasis, yin deficiency and so on.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R255.2

【参考文献】