中风醒脑液治疗气虚血瘀证后循环缺血性眩晕的临床观察

发布时间：2018-05-29 11:12

本文选题：中风醒脑液 + 气虚血瘀证　；参考：《成都中医药大学》2016年硕士论文

【摘要】：目的：通过对中风醒脑液治疗气虚血瘀证后循环缺血性眩晕患者的临床观察,对所得数据进行统计学分析,并评价其对气虚血瘀证后循环缺血性眩晕的治疗效果。方法：收集符合纳入标准的气虚血瘀证型后循环缺血性眩晕患者62例,按照随机、对照设计原则,其中治疗组33例,对照组29例,对照组为常规治疗组,治疗组采用在对照组的治疗基础上加用中风醒脑液,疗程为14天,治疗当天对所有患者进行三大常规、肝肾功能、血糖、电解质、血脂三项、血液流变学指标、凝血功能、头颅CT.TCD.心电图检测。根据患者症状和体征,详细记录中医症候眩晕的分级量化表、巴塞尔指数评分表,于治疗第14天时复查三大常规、肝肾功能、血脂三项、血液流变学指标、凝血功能、头颅CT及经颅TCD检查。记录治疗期间患者的不良反应及所采取的措施,运用SPSS.21统计软件分析所观察的指标。结果：①总体疗效：治疗后,治疗组的有效率为93.5%,对照组为72.4%,治疗组的疗效较对照组更明显(P0.05)。②血脂三项：治疗后,两组对血脂均无明显改善作用(P0.05)。③凝血四项：治疗后,两组均可改善APTT/TT/PT/FIB(P0.05),治疗组较对照组明显(P0.05)。④血液流变学：治疗后,两组均可改善血液流变学指标(P0.05),治疗组较对照组更明显(P0.05)。⑤TCD检查：治疗后,两组均可改善椎-基底动脉的平均血流速度(P0.01)和血管搏动指数(P0.05),但两组改善程度无差异性(P0.05)。⑥中医症候积分：治疗后,两组均可改善患者的中医症候积分(P0.05),但治疗组较对照组改善更明显(P0.05)。⑦巴塞尔指数评分：治疗后,两组均可提高患者的巴塞尔指数评分(P0.05),治疗组较对照组明显(P0.05)。⑧治疗前后安全性：两组对血常规、肝肾功能均无不明显的毒副作用及不良作用。结论：①中风醒脑液可提高总有效率。②中风醒脑液对血脂三项无明显改善作用。③中风醒脑液可改善凝血功能指标值。④中风醒脑液可改善血液流变学指标值。⑤中风醒脑液对TCD椎-基底动脉的Vm和PI无明显改善作用。⑥中风醒脑液可改善患者的中医症候积分。⑦中风醒脑液可提高患者的巴塞尔指数评分。⑧中风醒脑液安全性良好,对肝肾功能、血常规无毒副作用,且所用药物对患者无严重的不良反应,具有良好的应用前景。
[Abstract]:Objective: to observe the clinical effect of Xingnao fluid in treating circulation ischemic vertigo after qi deficiency and blood stasis syndrome, to analyze the data and to evaluate the therapeutic effect on circulation ischemic vertigo after qi deficiency and blood stasis syndrome. Methods: a total of 62 patients with posterior circulatory ischemic vertigo of Qi deficiency and Blood stasis Syndrome were collected. According to the principles of randomized and controlled design, 33 cases in treatment group, 29 cases in control group, and 29 cases in control group were selected as routine treatment group. The treatment group was treated with stroke Xingnao fluid on the basis of the treatment of the control group for 14 days. On the day of treatment, all patients were treated with three general methods: liver and kidney function, blood sugar, electrolyte, blood lipid, hemorheology index, coagulation function. Head CT.TCD. Electrocardiogram test. According to the symptoms and signs of the patients, the classification and quantification table of vertigo of TCM symptoms and signs, the Basel index score table were recorded in detail, and the three major routine, liver and kidney function, blood lipid, hemorheology and coagulation function were re-examined on the 14th day after treatment. Cranial CT and transcranial TCD. The adverse reactions and the measures taken during the treatment were recorded and the observed indexes were analyzed by SPSS.21 statistical software. Results the overall curative effect: after treatment, the effective rate of the treatment group was 93.55.The control group was 72.4. The curative effect of the treatment group was more obvious than that of the control group. Both groups were able to improve APTT / TT / PT / FIBN P0.05N, and the treatment group was significantly better than the control group in hemorheology: after treatment, both groups could improve the hemorheology index (P0.05), and the treatment group was more obvious than the control group in P0.05. 5TCD examination: after treatment, Both groups were able to improve the mean blood flow velocity of vertebrobasilar artery (P 0.01) and pulsatile index (P 0.05), but there was no difference in the improvement degree between the two groups. Both groups were able to improve the TCM symptom score of the patients (P 0.05), but the improvement of the treatment group was more obvious than that of the control group (P 0.05) and the Basel index score was higher than that of the control group. Both groups could improve the Basel index score (P0.05), and the safety of the treatment group was significantly higher than that of the control group (P 0.05.8) before and after treatment: there were no obvious side effects and adverse effects on blood routine examination, liver and kidney function in both groups. ConclusionThe total effective rate of 1 stroke Xingnao liquid can be increased. 2. No obvious improvement of blood lipids. 3. 3. Stroke Xingnao liquid can improve coagulation function index. 4. Stroke Xingnao liquid can improve hemorheology index value. 3. Stroke Xingnao liquid can improve coagulation function index. 4. Stroke Xingnao liquid can improve hemorheology index value. .5 there is no significant improvement in VM and Pi of TCD vertebrobasilar artery by stroke Xingnao liquid. 6. Stroke Xingnao liquid can improve TCM symptom score of patients. 7 stroke Xingnao fluid can improve patients' Basle Index score of stroke wake up. The brain fluid is safe, There are no toxic side effects on liver and kidney function, blood routine, and no serious adverse reactions of the drugs used in the patients, which has a good application prospect.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7

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