基于数据挖掘的古代痛经方药运用规律研究

发布时间：2018-05-29 23:16

本文选题：痛经 + 方药　；参考：《时珍国医国药》2017年04期

【摘要】：痛经为妇科常见病,严重影响女性生殖生理健康,中医药在其治疗方面积累丰富的经验。运用数据挖掘手段,以对痛经的治则治法及用药规律等进行探讨,从整体上认识痛经的病因病机、临证思路,为痛经中医药治疗提供指导。研究结果表明,关联规则提示,当归、白芍、川芎、肉桂、香附为痛经的常用药物及用药核心。LDA模型分析提示,痛经方药主要包括四个潜在主题,分为血虚血瘀、气滞血瘀、寒凝血瘀、气血两虚夹瘀四个证型。聚类分析提示痛经可分为8个聚类。从古籍文献研究结果提示补虚及活血化瘀为治疗古代治疗痛经的核心,"因瘀致痛"、"因虚致痛"为发病关键,活血化瘀、益气养血为治疗痛经的核心大法,用药宜补中有泄,标本兼治。古代痛经用药证治经验为现代痛经研究提供理论指导。
[Abstract]:Dysmenorrhea is a common gynecological disease, which seriously affects the reproductive health of women. Chinese medicine has accumulated rich experience in the treatment of dysmenorrhea. By means of data mining, this paper probes into the principles of dysmenorrhea and the law of drug use, so as to understand the etiology and pathogenesis of dysmenorrhea as a whole, and to provide guidance for the treatment of dysmenorrhea with traditional Chinese medicine. The results show that association rules, angelica, Radix Paeoniae Alba, Ligusticum chuanxiong, Cinnamomum cinnamon and Cyperus Cyperus are the common drugs used in dysmenorrhea and the drug core. LDA model analysis shows that the prescription of dysmenorrhea mainly includes four potential themes: blood deficiency and blood stasis, qi stagnation and blood stasis. Cold coagulation and blood stasis, two deficiency of qi and blood stasis four syndrome types. Cluster analysis showed that dysmenorrhea could be divided into 8 clusters. The research results of ancient literature indicate that tonifying deficiency and activating blood circulation and removing blood stasis are the core of treating dysmenorrhea in ancient times, "pain caused by blood stasis" and "pain caused by deficiency" are the key to the onset of dysmenorrhea. Promoting blood circulation and promoting qi and nourishing blood are the core methods of treating dysmenorrhea. Treat both symptoms and symptoms. The experience of treating dysmenorrhea in ancient times provides theoretical guidance for modern dysmenorrhea research.
【作者单位】：广州中医药大学;广东省中医院;
【基金】：广东省省级科技计划项目:面向传承发展中医药古籍文献本体知识库服务平台(No.2014A020221039) 广东省中医药局,广东省财政厅:中医药强省专项——2014年广东省名中医师承项目
【分类号】：R271.113

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