黄芪保心汤对心梗后心衰患者的临床疗效观察

发布时间：2018-06-04 13:18

本文选题：黄芪保心汤 + 心梗后心衰　；参考：《南京中医药大学》2017年硕士论文

【摘要】：目的:本研究通过观察临床心梗后心衰患者联合保心汤与未联合保心汤治疗前后其NYHA心功能分级改善情况、LVEF、LVEDd、六分钟步行距离、BNP以及生存质量和中医证候积分等数据,并将两组数据进行前后对比,总结出黄芪保心汤对于心梗后气阴两虚、瘀毒犯心证患者的临床疗效,以验证黄芪保心汤对于心梗后心衰病人发挥的改善心功能、缓解心衰症状、提高生存质量、改善预后等作用。方法:本实验总共入选70例患者,入选患者必须曾经或正在我院门诊治疗或住院治疗,并且明确诊断为心肌梗死合并心力衰竭,将他们随机分组(对照组35例、治疗组35例)。70例患者均接受西医综合治疗,治疗组患者额外接受保心汤中药治疗,连续观察3个月时间,收集70例患者治疗前后的NYHA、BNP、LVEF、LVEDd、六分钟步行距离等,并加以统计学处理,观察前后是否有统计学差异。结果:心功能方面:与对照组相比,治疗组的心功能分级改善更加明显(P0.05),LVEF、LVEDd均较治疗前改善,BNP降低较对照组更明显,6分钟步行距离治疗组增加更明显,且均有统计学差异(P0.05);生存质量方面:明尼苏达心衰生活质量评分及36条简明健康问卷均有改善,36条简明健康问卷两组对比差异性明显(P0.05);治疗组在改善中医证候积分上较对照组更优越(P0.05)。结论:黄芪保心汤为中药复方,可以改善心梗后心衰患者的心功能、提高生存质量,联合西药效果更加显著。
[Abstract]:Objective: to observe the improvement of NYHA cardiac function classification in patients with heart failure after myocardial infarction before and after treatment with Baoxin decoction and uncombined Baoxin decoction, and to observe the data of LVEFG LVEDd, 6-minute walking distance, quality of life and syndromes integral of traditional Chinese medicine (TCM). By comparing the data of the two groups before and after, the clinical effect of Huangqi Baoxin decoction on the patients with deficiency of Qi and Yin after myocardial infarction and blood stasis poisoning on heart syndrome was summarized in order to verify the effect of Huangqi Baoxin decoction on improving heart function and relieving symptoms of heart failure after myocardial infarction. Improve the quality of life, improve the prognosis and so on. Methods: a total of 70 patients were enrolled in this study. They must have been or were in our hospital for outpatient treatment or hospitalization, and were definitely diagnosed as myocardial infarction with heart failure. They were randomly divided into two groups (control group, 35 cases). In the treatment group, 35 patients were treated with western medicine, while the patients in the treatment group were treated with Baoxin decoction for 3 months, and 70 patients were collected before and after treatment, and the walking distance of six minutes was analyzed statistically. Whether there is statistical difference before and after observation. Results: compared with the control group, the improvement of cardiac function grading in the treatment group was more obvious than that in the control group. The improvement of BNP in the treatment group was more obvious than that in the control group, and the increase in the treatment group was more obvious than that in the control group, and the improvement of BNP in the treatment group was more obvious than that in the control group. There were significant differences in quality of life between the two groups: Minnesota Heart failure score and 36 brief health questionnaires were improved and 36 simple health questionnaires were improved. The treatment group improved TCM syndrome. Compared with the control group, it was superior to the control group (P 0.05). Conclusion: Huangqi Baoxin decoction can improve heart function and quality of life of patients with heart failure after myocardial infarction.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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