针刺调肝法为主治疗女性痤疮的临床疗效观察

发布时间：2018-06-04 15:13

本文选题：女性痤疮 + 针刺调肝法　；参考：《成都中医药大学》2016年硕士论文

【摘要】：目的：通过临床随机对照试验,观察针刺调肝法为主与口服西药对治疗女性痤疮的皮损、全身症状、生活质量影响差异的比较,从而评价针刺调肝法治疗女性痤疮的综合疗效,为临床针刺治疗女性痤疮提供更多思路。方法：采取随机对照分组的方法,将60例符合纳入标准的合格受试者分为治疗组和对照组各30例。在每日2次皮损处外擦克林霉素磷酸酯凝胶和生活调护的基础上,治疗组施以针刺调肝法治疗,隔天1次,20天为1疗程,连续2个疗程。对照组予以口服异维A酸软胶囊,按体重分为大于50kg,1天3次,或体重小于50kg,1天2次,每次均服10mg,共计40天。观察评定治疗前后的皮损症状、全身症状及面部痤疮特异性生活质量量表评分,通过各项指标对比,运用统计学软件分析结果,进行疗效评价。结果：1.两组治疗前基线情况比较包括年龄、病程、皮损严重程度分级、皮损症状评分、全身症状评分以及面部痤疮特异性生活质量量表评分,经统计学分析,结果无明显差异(P0.05),具有可比性。2.调肝法针刺组与西药组治疗后的皮损、全身症状以及面部痤疮特异性生活质量改善水平与治疗前比较有统计学差异(P0.05)；两组治疗后进行组间皮损症状评分差值、全身症状评分差值比较,差异具有统计学意义(P0.05),而面部痤疮特异性生活质量评分差值比较,差异则无统计学意义(P0.05),提示生活质量程度提高相当。3.治疗结束后,调肝法针刺组总有效率为92.9%,口服西药组总有效率为82.8%,两组总体疗效比较差异有统计学意义(P0.05)。结论：1.针刺调肝法与口服西药对女性痤疮治疗均有效,且针刺调肝法优于口服西药,两者的安全性和依从性均较好。2.针刺调肝法在改善患者皮损严重程度及全身症状方面优于口服西药,在改善患者生活质量方面疗效相当。
[Abstract]:Objective: to observe the effects of acupuncture and liver regulating therapy on acne lesions, systemic symptoms and quality of life (QOL) in female acne patients, and to evaluate the comprehensive effect of acupuncture and liver regulating therapy on female acne. To provide more ideas for clinical acupuncture treatment of female acne. Methods: 60 eligible subjects were divided into treatment group (n = 30) and control group (n = 30). On the basis of external brushing clindamycin phosphate gel and daily nursing care, the treatment group was treated with acupuncture and liver regulating method, every other day for 20 days as a course of treatment, two consecutive courses of treatment. The control group was treated with isotinic acid soft capsules. According to their body weight, they were divided into 3 times or less than 50 kg / day for 3 times or less than 50 kg / d, 10 mg / time for 40 days. To observe and evaluate the symptoms of skin lesions, systemic symptoms and facial acne specific quality of life scale score before and after treatment, through the comparison of various indicators, using statistical software analysis results, to evaluate the efficacy. The result is 1: 1. The baseline data of the two groups before treatment included age, course of disease, grade of severity of skin lesion, score of skin lesion symptom, score of systemic symptoms and score of facial acne specific quality of life scale. Results there was no significant difference (P 0.05). There were significant differences in skin lesions, systemic symptoms and specific quality of life (QOL) of facial acne between the two groups after treatment (P 0.05), and the difference in the score of skin lesions between the two groups after treatment. The difference of general symptom score was statistically significant (P 0.05), but the difference of facial acne specific quality of life score was not statistically significant (P 0.05), indicating that the quality of life was improved by 3%. After the treatment, the total effective rate of acupuncture group was 92.9 and that of oral western medicine group was 82.8.The difference between the two groups was statistically significant (P 0.05). Conclusion 1. Acupuncture regulating liver method and oral western medicine are both effective in the treatment of female acne, and acupuncture regulating liver method is better than oral western medicine. The safety and compliance of both methods are good. 2. Acupuncture and liver regulating method is superior to oral western medicine in improving the severity of skin lesions and systemic symptoms, and has the same effect in improving the quality of life of patients.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.7

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