加味无比山药丸治疗Ⅲ级慢性阻塞性肺疾病稳定期（脾肾两虚,肾不纳气）的临床研究

发布时间：2018-06-06 07:05

  本文选题：加味无比山药丸 + COPD　； 参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:拟通过临床观察加味无比山药丸对III级慢性阻塞性肺疾病稳定期(脾肾两虚,肾不纳气)的临床治疗效果,探讨其是否可以改善患者临床症状、活动能力,提高患者生活质量,从而进一步验证COPD进展和急性加重在于稳定期的肺脾肾三脏关系是否协调,能否维持浊气的生成和排出的平衡。方法:本实验选择符合纳入标准的门诊及住院的III级慢性阻塞性肺疾病稳定期(脾肾两虚,肾不纳气)的患者60例,随机分为中药治疗(加味无比山药丸)组与西药对照组(天晴速乐吸入剂),每组各30例,两组比例为1:1。通过对气短、喘促等症状、呼吸困难指数、六分钟步行试验前后变化情况的评估,比较治疗组和对照组的疗效差异,最终得出客观的结论。结果:治疗组的总体有效率为93.333%,对照组的总体有效率83.333%(P0.05),提示治疗组疗效明显对照组。加味无比山药丸对于患者气短、喘促症状的改善方面与西药相似,但在食少腹胀、四肢凉冷的次症以及呼吸困难指数、六分钟步行试验的改善方面优于西药组。结论:临床研究表明加味无比山药丸对于慢性阻塞性肺疾病稳定期(脾肾两虚,肾不纳气)疗效确切,相似于西药治疗,但在改善临床症状方面疗效优于对照组,而且毒副作用小,用药经济,进一步验证COPD稳定期的治疗在于协调肺脾肾三脏关系,维持浊气的生成和排出的平衡。完善了导师王檀教授治疗本病的理论。
[Abstract]:Objective: to observe the clinical therapeutic effect of Jiawei Huishan pill on III grade chronic obstructive pulmonary disease in stable period (spleen and kidney deficiency, kidney deficiency), and to explore whether it can improve the clinical symptoms and activity ability of the patients. Improve the quality of life of patients so as to further verify that the progression and acute exacerbation of COPD lies in the stable phase of lung spleen and kidney three visceral relationship whether to maintain the balance of turbid qi generation and expulsion. Methods: sixty patients with III grade chronic obstructive pulmonary disease (III) in stable stage (spleen and kidney deficiency, kidney failure), who met the criteria included in the study, were selected. They were randomly divided into traditional Chinese medicine treatment group and western medicine control group with 30 cases in each group. The ratio of the two groups was 1: 1. By evaluating the symptoms of shortness of breath, dyspnea index and changes before and after the six-minute walking test, the curative effects of the treatment group and the control group were compared, and the objective conclusion was reached. Results: the total effective rate of the treatment group was 93.3333.The total effective rate of the control group was 83.3330.The results indicated that the curative effect of the treatment group was obvious in the control group. The improvement of symptoms of dyspnea and dyspnea was similar to that of western medicine, but it was better than that of western medicine group in the improvement of food and abdominal distension, cold limbs, dyspnea index and 6-minute walking test. Conclusion: the clinical study shows that Jiawei Huishan pill is effective in the stable stage of chronic obstructive pulmonary disease (spleen and kidney deficiency, kidney deficiency), similar to western medicine treatment, but the curative effect in improving clinical symptoms is better than that in control group. Furthermore, the treatment of COPD in stable period is to coordinate the relationship between lung, spleen and kidney, and to maintain the balance of turbid gas generation and excretion. Improved the tutor Professor Wang Tan's theory of treating this disease.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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