瑶药星毛冠盖藤正丁醇部位化学成分研究

发布时间：2018-06-08 03:24

  本文选题：冠盖藤 + 化学成分　； 参考：《中国药学杂志》2017年18期

【摘要】：目的对瑶药"肿瘤藤"即星毛冠盖藤(Pileostegia tomentella Hand.-Mazz.)藤茎的化学成分进行研究。方法利用各种色谱方法进行分离纯化,根据理化性质和NMR,MS等波谱技术鉴定化合物的结构。结果从星毛冠盖藤藤茎甲醇提取物中的正丁醇萃取部位分离鉴定了13个化合物,分别为1-O-(β-D-glucosyl)-2-[2-methoxy-4-(ω-hydroxypropyl)phenoxy]propan-3-ol(1),(+)-lyoniresinol-3a-O-β-D-glucopyranoside(2),紫丁香苷(syringin)(3),柏松苷(coniferin)(4),二氢柏松苷(dihydroconiferin)(5),but-3-enyl-β-D-glucoside(6),4-(2,3-dihydroxypropyl)-2,6-dimethoxy phenyl-β-D-glucopyranoside(7),nikoenoside(8),原儿茶酸乙酯(protocatechuic acid ethyl ester)(9),8-甲氧基香豆素-7-O-β-D-葡萄糖(8-methoxy coumarin-7-O-β-D-glucopyranoside)(10),6-O-R-L-rhamnopyranosyl-β-D-glucopyranoside methyl salicylate(11),烟酰胺(nicotinamide)(12)和3,5-二咖啡酰奎宁酸甲酯(3,5-di-O-caffeoyl quinicacid methyl ester)(13)。结论所有化合物均为首次从该属和该植物中分离得到。
[Abstract]:Objective to investigate the effect of the Yao medicine, "Oncology Rattan", on Pileostegia tomentella Hand.-Mazz. The chemical constituents of the stem of rattan were studied. Methods the compounds were separated and purified by various chromatographic methods. The structures of the compounds were identified according to their physicochemical properties and NMRMS spectra. Results 13 compounds were isolated and identified from methanol extracts from the stem of Dioscorea angustifolia. 鍒嗗埆涓，

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