推拿配合功能锻炼治疗膝关节骨性关节炎的临床观察

发布时间：2018-06-09 23:16

本文选题：功能锻炼 + 推拿　；参考：《南京中医药大学学报》2017年04期

【摘要】：目的观察推拿配合功能锻炼治疗膝关节骨性关节炎(KOA)的临床效果。方法选取2016年1月-2016年12月我院收治的180例KOA患者,将其按照随机数字法随机分为观察组A、观察组B和对照组,每组60例,对照组给予规范化的功能锻炼,观察组A在对照组基础上给予中医特色的推拿手法进行治疗,2组均治疗2周,观察组B在对照组基础上给予硫酸氨基葡萄糖胶囊治疗。分别于治疗前后对膝关节肿胀、压痛、活动受限评分及Lysholm膝关节功能进行评分,且分别于治疗前后抽取患者膝关节关节液,检测基质金属蛋白酶-3(MMP-3)、基质金属蛋白酶组织抑制因子-1(TIMP-1)和肿瘤坏死因子-α(TNF-α),并对2组治疗后的临床疗效和治疗期间的安全性进行评价。结果治疗后3组膝关节肿胀、压痛、活动受限评分均显著降低(P0.05),Lysholm膝关节功能评分均显著升高(P0.05),但观察组A和观察组B膝关节肿胀、压痛、活动受限评分降低更为明显(P0.05),Lysholm膝关节功能评分升高更为明显(P0.05)。治疗后3组MMP-3、TIMP-1及TNF-α水平均显著降低(P0.05),但观察组A和观察组B降低更为明显(P0.05)。治疗后观察组A和观察组B的总有效率分别为95.00%和91.67%显著高于对照组的75.00%,差异具有统计学意义(!2=9.412、8.757,P0.01)。3组患者均未出现明显不良反应,安全级别均为Ⅰ级。结论推拿配合功能锻炼治疗KOA临床疗效显著,安全性高,值得临床推广。
[Abstract]:Objective To observe the clinical effect of massage combined with functional exercise in the treatment of osteoarthritis of knee joint (KOA). Methods 180 patients with KOA in our hospital in January 2016 -2016 December were randomly divided into the observation group A, the observation group B and the control group, 60 cases in each group, the standardized functional exercise was given to the group, and the observation group A was in the control. The group was treated with traditional Chinese medicine massage on the basis of traditional Chinese medicine. The 2 groups were treated for 2 weeks. The observation group B was given Glucosamine Sulfate Capsules treatment on the basis of the control group. The knee joint swelling, the pressure pain, the limited activity score and the Lysholm knee function were evaluated before and after the treatment, and the knee joint clearance was taken before and after the treatment. The solution was used to detect matrix metalloproteinase -3 (MMP-3), matrix metalloproteinase tissue inhibitor -1 (TIMP-1) and tumor necrosis factor - alpha (TNF- alpha). The clinical efficacy and safety of the 2 groups were evaluated. Results after treatment, 3 groups of knee joint swelling, pressure pain, and activity limited score were significantly decreased (P0.05), Lysholm knee joint. The score of function increased significantly (P0.05), but the swelling of B knee joint in the observation group and the observation group were more obvious (P0.05), and the score of Lysholm knee joint function increased more significantly (P0.05). The levels of MMP-3, TIMP-1 and TNF- alpha in the 3 groups were significantly decreased (P0.05), but the B reduction was more obvious in the observation group and the observation group. After treatment, the total effective rate of A and B in observation group was 95% and 91.67% significantly higher than that of control group 75%. The difference was statistically significant (! 2=9.412,8.757, P0.01) group.3 patients had no obvious adverse reaction, the safety level was grade I. Conclusion massage combined with functional exercise treatment of KOA has significant clinical efficacy, high safety, and worthy of treatment. Bed promotion.
【作者单位】：南京市中心医院康复科;
【分类号】：R244.1

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