期门穴定点超声肝内解剖结构的比较研究

发布时间：2018-06-10 16:50

本文选题：慢性乙型肝炎 + 脂肪肝　；参考：《辽宁中医药大学》2017年硕士论文

【摘要】：目的:通过对肝脏内部不同病变患者及健康志愿者,肝区期门穴彩色多普勒超声定点检测的穴下解剖组织结构的差异性比较研究,从解剖组织形态学角度探索肝区内期门穴反映肝脏病理变化的生物医学基础。为论证肝募期门反映病症效应及其相关的特定穴理论的科学性提供科学依据。材料与方法:对象及分组:收集病变部位在肝脏的慢乙肝、肝硬化、脂肪肝患者病例114例,健康志愿者资料45例。疾病组采用分层分组的方法,分为慢乙肝组、肝硬化组和脂肪肝组。指标检测及方法:采用低频彩色超声定点垂直超声检测方法,检测在肝区的期门穴下解剖组织结构,以彩超视野中点为原点,记录距离原点最近的肝内组织形态结构,总结并汇总数据。分别进行肝脏不同疾病状态受试者,解剖组织结构检出率的组间配对检验,以健康对照组为基准,探讨期门穴定点超声所揭示的HBV感染不同病理阶段、脂肪肝的肝脏内部组织形态学的病理变化规律及特征。使用统计学分析软件SPSS17.0对采集的数据进行分析,均值用(?x±s)表示,如检验结果P0.05说明具有统计学意义。结果:1.健康组与肝内病变组配对检验结果(1)慢乙肝、肝硬化肝组织检出率低于健康组,门静脉血管检出率高于健康组,P0.05(2)脂肪肝矢状部检出率高于健康组,P0.05;2.肝内病变组间配对检验结果(1)慢乙肝门静脉检出率高于肝硬化、脂肪肝,P0.05,(2)慢乙肝、肝硬化肝组织检出率小于脂肪肝,P0.05,结论:1.期门穴对应的肝脏内部解剖组织结构的差异性是影响期门穴反映病症效应特异性的生物医学基础。2.慢乙肝、肝硬化不同病理阶段门静脉干支、矢状部检出率增高,符合HBV感染之后,会出现肝组织纤维化导致门静脉高压,以及有肝脏体积变小的病理演变规律。体现了“肝以血为用”中医理论的科学性。
[Abstract]:Objective: to compare the differences of anatomical tissue structure of subpoints detected by color Doppler ultrasound at portal acupoints in different liver lesions and healthy volunteers. From the angle of anatomical histomorphology, we explored the biomedical basis of portal point in liver region to reflect the pathological changes of liver. It provides a scientific basis for demonstrating the effect of liver disease and its related theory of specific acupoints. Materials and methods: 114 patients with chronic hepatitis B, liver cirrhosis and fatty liver were collected and 45 healthy volunteers were collected. The disease group was divided into chronic hepatitis B group, liver cirrhosis group and fatty liver group. Indexes and methods: low frequency color ultrasound was used to detect the anatomical structure of liver tissue under the point of stage gate. The middle point of the field of vision of color Doppler ultrasound was used as the origin to record the structure of the liver tissue nearest to the origin. Summarize and summarize data. The detection rate of anatomical tissue structure of different liver diseases in subjects was tested by paired group, and the pathological stages of HBV infection revealed by sentinel ultrasound at portal acupoint were studied by using the healthy control group as the reference. Pathological changes and characteristics of liver histomorphology in fatty liver. The statistical analysis software SPSS 17.0 was used to analyze the collected data, the mean value was expressed by X 卤s, such as the test results P0.05 showed statistical significance. The result is 1: 1. 1) the detection rate of chronic hepatitis B and liver cirrhosis in liver tissue was lower than that in healthy group, and the detection rate of portal vein was higher than that in healthy group (P0.05 / 2) the sagittal detection rate of fatty liver was higher than that in healthy group. The detection rate of chronic hepatitis B in portal vein was higher than that in liver cirrhosis, and that in fatty liver tissue was lower than that in fatty liver tissue. The difference of the anatomical structure of the liver corresponding to the point gate is the biomedical basis that affects the specificity of the disease effect at the point gate. The detection rate of portal vein dry branch in different pathological stages of chronic hepatitis B and liver cirrhosis was higher than that in sagittal part, which was consistent with the pathological evolution of hepatic fibrosis and portal hypertension after HBV infection. It reflects the scientific nature of traditional Chinese medicine theory of "liver is used by blood".
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R246.1

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