隔物灸治疗原发性痛经的系统评价

发布时间：2018-06-24 14:18

本文选题：隔物灸 + 系统评价　；参考：《成都中医药大学》2016年硕士论文

【摘要】：目的：使用系统评价分析的方法,评价隔物灸对原发性痛经的临床疗效和安全性。方法：根据目的制定了文献的纳入及排除标准,制定检索策略,综合检索CBM、 CNKI、维普数据库、万方会议论文数据库、The Cochrane Library、PubMed等,检索时间为2000年到2016年3月。通过阅读题目、摘要、参考文献、全文的方式,严格筛选出此中契合纳入标准的临床随机对照试验(RCTs),对最终纳入的文献研究进行相关数据提取,制成Excel表格。对纳入的各研究的方法学质量进行评价,数据分析合成,和meta-分析,对研究进行结局指标的定量和定性分析,并对结果证据质量进行GRADE评级。客观地评价隔物灸对原发性痛经的临床疗效及其安全性。结果：本系统评价共纳入12篇以隔物灸为干预措施的临床随机对照实验,共1236例受试者,其中隔物灸组659例,对照组637例,年龄约14-28岁,病程6月-数年不等。隔物灸组与对照组的7个结局指标进行定量分析结果分别为：总有效率[RR1.15,95%CI(1.11,1.20)],隔物灸VS西药组有效率[RR1.1895%CI (1.10,1.27)],隔物灸VS中成药组有效率[RR 1.13,95%CI (1.08,1.19)],总治愈率[RR 1.81,95%CI(1.57,2.09)],隔物灸VS西药组治愈率[RR 2.11,95%CI (1.37,3-25)],隔物灸VS中成药组治愈率[RR1.71,95%CI (1.44,2.01)],痛经临床症状积分[MD-1.96,95%CI (-2.94,-0.99)]。结论：1、隔物灸与西药组、中成药组、中药组对比,在临床疗效的有效率与治愈率方面具有更好的效果,证据质量中级,结果稳定。2、痛经临床症状积分的评价方面：分析结果证明隔物灸比对照组有更好效果,但证据治疗不高,结果需谨慎对待。
[Abstract]:Objective: to evaluate the clinical efficacy and safety of moxibustion on primary dysmenorrhea. Methods: according to the objective, the inclusion and exclusion criteria of the literature were formulated, the retrieval strategy was formulated, the CBM, CNKI, Wiper database, the Cochrane Library PubMed database and so on were searched synthetically. The retrieval time was from 2000 to 2016. By means of reading title, abstract, reference document and full text, the clinical randomized controlled trial (RCTs), which fit into the standard of inclusion, was selected strictly, and the relevant data were extracted from the final literature research, and the Excel table was made. Evaluation of the methodological quality of the included studies, data analysis synthesis, and meta-analysis, quantitative and qualitative analysis of the outcome indicators of the study, and grade rating of the quality of the results and evidence. Objective to evaluate the clinical efficacy and safety of moxibustion on primary dysmenorrhea. Results: a total of 12 clinical randomized controlled trials with moxibustion separated as intervention measures were included in this system. 1236 subjects were involved, including 659 cases in moxibustion group and 637 cases in control group, aged 14-28 years. The course of disease ranged from 6 months to several years. The results of quantitative analysis of seven outcome indexes in moxibustion group and control group were as follows: total effective rate [RR1.1595 CI (1.111.20)], moxibustion separated moxibustion vs western medicine group (RR1.1895 CI (1.101.27), moxibustion with separated moxibustion vs Chinese patent medicine group (RR 1.139595 CI (1.081.19), total cure rate (RR 1.8195 95 CI (1.572.09)] The cure rate of the group [RR 2.1195: CI (1.37 ~ 3-25)], the cure rate of the group of separated moxibustion with vs [RR1.71 ~ 9595 CI (1.44m2.01)], the clinical symptom score of dysmenorrhea [MD-1.96 ~ 9595 CI (-2.94-0.99)]. Conclusion compared with the western medicine group, the traditional Chinese medicine group and the traditional Chinese medicine group, the effective rate and cure rate of the moxibustion are better than those of the western medicine group, the Chinese patent medicine group and the traditional Chinese medicine group, and the quality of the evidence is intermediate. Results stable. 2. The evaluation of clinical symptom integral of dysmenorrhea: the result of analysis proved that moxibustion separated by substance had better effect than that of control group, but the evidence treatment was not high, the result should be treated with caution.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.3

【参考文献】