颈椎旋转手法对兔粥样斑块期颈动脉拉伸力学性能的影响

发布时间：2018-06-25 00:24

本文选题：颈椎旋转手法 + 颈动脉　；参考：《医用生物力学》2017年03期

【摘要】：目的探讨颈椎旋转手法对兔粥样斑块期颈动脉拉伸力学性能的影响。方法选取30只健康的雄性新西兰大耳兔,随机分为实验组、模型对照组和空白对照组。实验组对兔进行颈动脉粥样硬化斑块造模及颈椎旋转手法干预,模型对照组仅进行颈动脉粥样硬化斑块造模,而空白对照组不进行任何干预。观测3组兔在不同干预后颈动脉各项拉伸力学性能指标的差异。结果实验组与模型对照组以及空白对照组比较,最大应变、最大载荷和生理性弹性模量均有统计学差异(P0.05);实验组最大应变比模型对照组、空白对照组分别小24.87%、52.09%;实验组最大载荷分别是模型对照组、空白对照组的2.21、3.47倍;实验组生理性弹性模量分别是模型对照组、空白对照组的1.60、1.89倍。结论相对正常颈动脉而言,颈动脉粥样硬化斑块的存在会降低颈动脉的拉伸力学性能,而对存在颈动脉粥样硬化的兔进行颈椎旋转手法操作,会进一步降低颈动脉的拉伸力学性能。因此,临床上对于存在颈动脉粥样硬化斑块的患者,最好避免进行颈椎旋转手法操作。
[Abstract]:Objective to investigate the effect of cervical rotation manipulation on tensile mechanical properties of carotid artery in atherosclerotic plaque rabbits. Methods 30 healthy male New Zealand rabbits were randomly divided into three groups: experimental group, model control group and blank control group. In the experimental group, the carotid atherosclerotic plaque model and the cervical spine rotation intervention were carried out in the experimental group. The model control group only made the carotid atherosclerotic plaque model, while the blank control group did not intervene. The differences of tensile mechanical properties of carotid artery in three groups were observed after different intervention. Results compared with the model control group and the blank control group, the maximum strain, maximum load and physiological modulus of elasticity in the experimental group were significantly different (P0.05), and the maximum strain ratio of the experimental group to the model control group was significant (P0.05). The maximum load in the experimental group was 2.21 times of that in the model control group and 2.21 times in the blank control group, and the physiological modulus of elasticity in the experimental group was 1.60 ~ 1.89 times of that in the model control group and the blank control group, respectively. Conclusion compared with the normal carotid artery, the presence of carotid atherosclerotic plaque may decrease the tensile mechanical properties of carotid artery, while the cervical spine rotation manipulation can be performed on the rabbits with carotid atherosclerosis. It will further reduce the tensile mechanical properties of carotid artery. Therefore, for patients with carotid atherosclerotic plaques, it is best to avoid cervical rotation manipulation.
【作者单位】：南方医科大学中医药学院;
【基金】：国家自然科学基金项目(81273871)
【分类号】：R244.1

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