破血化瘀填精补髓法治疗出血性中风后轻度认知功能损害的临床研究

发布时间：2018-06-25 23:39

本文选题：出血性中风后轻度认知功能损害 + 破血化瘀、填精补髓　；参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:通过临床研究,评价破血化瘀、填精补髓法治疗出血性中风后轻度认知功能损害的临床疗效。方法:筛选符合出血性中风后轻度认知功能损害诊断的患者72例,随机分为两组,治疗组采用中药治疗方案,对照组给予尼莫地平片,疗程均为3个月。应用认知评定量表和中医核心症状观察量表评价两组治疗效果。结果:1.治疗3个月后,中药治疗组与对照组总疗效(ADAS-cog、中医核心症状)在总有效率和显效率方面,两组比较具有明显差异(P0.05)。2.在改善ADAS-cog积分比较上,治疗组组内比较有显著性差异(P0.05),对照组有明显差异(P0.05),两组组间比较差异具有统计学意义(P0.05)。3.在中医核心症状总积分比较上,治疗组组内比较有显著性差异(P0.05),对照组无明显差异(P0.05),两组组间比较差异具有统计学意义(P0.05)。提示中药治疗组在改善患者ADAS-cog与中医核心症状积分方面均有疗效,明显优于对照组。结论:1.破血化瘀填精补髓法能够有效改善出血性中风后轻度认知功能损害患者的认知水平。2.破血化瘀填精补髓法能够有效改善出血性中风后轻度认知功能损害患者的临床症状,其中主要包括记忆力障碍(言谈不知首尾,转盼遗忘,思量不能等)、言语障碍(言善误,言语懒,多言不定,言语如凝、言语重复等)、情感障碍(居暗避人,兴趣索然,忧愁思虑等)及肢体障碍(肢体笨拙,步履迟重)。
[Abstract]:Objective: to evaluate the clinical effect of breaking blood and removing blood stasis and filling essence and reinforcing marrow in the treatment of mild cognitive impairment after hemorrhagic apoplexy. Methods: a total of 72 patients with mild cognitive impairment after hemorrhagic stroke were selected and randomly divided into two groups: the treatment group was treated with traditional Chinese medicine and the control group was given nimodipine tablets for 3 months. The therapeutic effects of the two groups were evaluated by using the cognitive rating scale and the observation scale of the core symptoms of traditional Chinese medicine. The result is 1: 1. After 3 months of treatment, the total efficacy (ADAS-cog) of the Chinese medicine treatment group and the control group (ADAS-cog) in the total effective rate and effective rate, there was significant difference between the two groups (P0.05). 2. In improving ADAS-cog score comparison, the treatment group has significant difference (P0.05), the control group has a significant difference (P0.05), the comparison between the two groups has statistical significance (P0.05). 3. On the total integral comparison of TCM core symptoms, the treatment group had significant difference (P0.05), the control group had no significant difference (P0.05), the difference between the two groups was statistically significant (P0.05). The results suggest that the treatment group has better effect than the control group in improving ADAS-cog and the score of core symptoms of TCM. Conclusion 1. The method of breaking blood and removing blood stasis and filling up marrow can effectively improve the cognitive level of patients with mild cognitive impairment after hemorrhagic apoplexy. The method of breaking blood and removing blood stasis and filling essence and nourishing marrow can effectively improve the clinical symptoms of patients with mild cognitive impairment after hemorrhagic stroke, which mainly include memory disorder (talking without knowing the beginning and end, turning to oblivion, thinking, etc.), speech disorder (good speech, false speech, etc.) Sloth, indeterminacy, speech, repetition, etc.), emotional disorders (avoidance, lack of interest, anxiety, etc.) and physical disorders (clumsy limbs, late steps).
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7

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