电针治疗良性前列腺增生及对患者雌雄激素水平的影响

发布时间：2018-06-26 07:49

本文选题：良性前列腺增生 + 电针　；参考：《中国针灸》2017年06期

【摘要】：目的:探讨电针对良性前列腺增生患者的疗效及对激素水平的影响。方法:将60例患者随机分为电针组和药物组,每组30例。电针组采用电针中极、曲骨穴治疗,每日1次,每周5次;药物组口服盐酸坦洛新缓释胶囊0.2 mg,每日1次,两组均治疗6周。观察两组治疗前后血清睾酮(T)、雌二醇(E_2)水平及雌雄激素比(E_2/T)的变化,采用国际标准进行前列腺症状评分(IPSS)及阴茎勃起功能评分(IIEF5),并检测血清前列腺特异抗原(PSA)及两组患者的不良反应情况,比较两组的临床疗效。结果:电针组治疗前后血清T、E_2、E_2/T比较差异均无统计学意义(均P0.05),药物组治疗前后E_2/T比较差异有统计学意义(P0.05);两组间血清T、E_2、E_2/T比较差异均无统计学意义(均P0.05)。电针组IPSS评分较治疗前降低(P0.05),药物组IPSS评分与治疗前比较差异无统计学意义(P0.05);治疗后电针组IPSS评分低于药物组(P0.05);电针组治疗后症状严重者明显减少,整体情况优于药物组(P0.05)。两组IIEF5评分、PSA值治疗前后及组间比较差异均无统计学意义(均P0.05)。电针组总有效率为60.7%(17/28),明显优于药物组的30.8%(8/26,P0.05)。结论:电针中极、曲骨穴能明显减轻患者临床症状,疗效优于口服盐酸坦洛新缓释胶囊,对患者血清T、E_2水平未见明显影响。
[Abstract]:Objective: to investigate the effect of electroacupuncture on benign prostatic hyperplasia (BPH) and its effect on hormone level. Methods: 60 patients were randomly divided into electroacupuncture group and drug group with 30 cases in each group. The patients in the electroacupuncture group were treated with electroacupuncture at the middle pole and flexure bone points, once a day, 5 times a week, and in the drug group, 0.2 mg of Tanluoxin Hydrochloride sustained release capsule was taken orally, once a day, for 6 weeks in both groups. The changes of serum testosterone (T), estradiol (Eti2) and estradiol ratio (ESP / T) before and after treatment were observed in the two groups. Prostate symptom score (IPSS) and penile erectile function score (IIEF5) were evaluated by international standard. Serum prostate specific antigen (PSA) and adverse reactions of the two groups were detected and the clinical efficacy of the two groups was compared. Results: there was no significant difference between the two groups before and after treatment (P0.05), but there was no significant difference between the two groups before and after treatment (P0.05), and there was no significant difference between the two groups (P0.05). The IPSS score of electroacupuncture group was lower than that before treatment (P0.05), the IPSS score of drug group was not significantly different from that before treatment (P0.05); the IPSS score of electroacupuncture group was lower than that of drug group after treatment (P0.05); the severity of symptoms in electroacupuncture group was significantly lower than that of drug group (P0.05), and the overall situation was better than that of drug group (P0.05). There was no significant difference in IIEF5 score and PSA between the two groups before and after treatment (P0.05). The total effective rate of electroacupuncture group was 60.7% (17 / 28), which was significantly better than that of drug group (30.8%) (8 / 26 P 0.05). Conclusion: electroacupuncture at the middle pole and flexure bone point can obviously relieve the clinical symptoms of the patients, and the curative effect is better than that of tanluoxin hydrochloride sustained-release capsules, but there is no obvious effect on the serum TX E 2 level of the patients.
【作者单位】：北京中医药大学东方医院针灸科;
【基金】：北京中医药大学东方医院“东方新星”人才培养项目
【分类号】：R246.9

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