中药治疗女童乳房早发育临床观察

发布时间：2018-06-27 00:45

本文选题：中药治疗 + 乳房早发育　；参考：《辽宁中医杂志》2017年11期

【摘要】：目的:观察中药治疗女童乳房早发育的临床疗效。方法:将90例单纯乳房早发育女童按随机数字表法分为观察组和对照组各45例。对照组以改善饮食结构及生活习惯进行干预,观察组在此基础上以知柏地黄丸化裁治疗,3个月为1个疗程,治疗1~2个疗程,随访6~12个月。观察两组患儿治疗前后症状体征变化及不良反应情况。结果:观察组和对照组总有效率分别为88.9%和68.9%,观察组疗效优于对照组,差异有统计学意义(P0.05);观察组中枢性性早熟转化率为2.2%,低于对照组13.3%。随访中,两组患儿均未出现明显不良反应。结论:中药治疗女童乳房早发育能够促进患儿乳房肿块消退,降低中枢性性早熟的转化率,安全有效。
[Abstract]:Objective: to observe the clinical effect of traditional Chinese medicine on early breast development in girls. Methods: 90 girls with simple breast premature development were randomly divided into observation group (n = 45) and control group (n = 45). In the control group, the diet structure and living habits were improved, and the observation group was treated with Zhibai Dihuang pills, 3 months as a course of treatment, 1 ~ 2 courses of treatment, and followed up for 6 ~ 12 months. The changes of symptoms and signs and adverse reactions were observed before and after treatment. Results: the total effective rates of the observation group and the control group were 88.9% and 68.9%, respectively. The curative effect of the observation group was better than that of the control group, the difference was statistically significant (P0.05), and the central precocious puberty rate in the observation group was 2.2%, lower than that in the control group (13.3%). No significant adverse reactions were observed in the two groups during follow-up. Conclusion: the treatment of early breast development in girls with traditional Chinese medicine can promote the regression of breast masses, reduce the conversion rate of central precocious puberty, and be safe and effective.
【作者单位】：大连医科大学研究生院;大连医科大学附属大连市儿童医院中医科;
【基金】：大连市医学卫生科学研究计划(2014064)
【分类号】：R272

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