疏肝和胃降逆法治疗原发性胆汁反流性胃炎（肝气犯胃证）的临床观察

发布时间：2018-06-28 01:45

本文选题：原发性胆汁反流性胃炎 + 肝气犯胃证　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：研究目的:通过运用疏肝和胃降逆法对原发性胆汁反流性胃炎(肝气犯胃证)的治疗,探讨其临床疗效。研究方法:选择符合原发性胆汁反流性胃炎(肝气犯胃证型)患者50例,均在2016年1月至2017年1月就诊于黑龙江中医药大学附属第一医院门诊,入选50例患者给予疏肝和胃降逆法(主要药物组成:醋炙柴胡、枳壳、炒白术、厚朴、金钱草等)进行治疗,将药物加水约400毫升,浸泡1小时,煎15-20分钟,取汁;二煎加水400毫升,取汁;二煎混合,分早晚饭前两次温服,连服8周。8周后进行治疗前后对照,观察患者的临床疗效、症状积分、胃镜的变化,对结果进行统计学分析。结果:疏肝和胃降逆法对原发性胆汁反流性胃炎(肝气犯胃证)的治疗,临床总有效率为91.49%,治疗胃黏膜相的总有效率是93.61%,治疗胆汁返流的总有效率是95.74%,中医证候总有效率是91.49%。在中医证候总积分方面,治疗后较治疗前显著下降(P0.01)。在中医证候单项积分方面,治疗后在患者胃痛或痛窜两胁;胃脘痞满;情志不畅;反酸、烧心;口苦、口臭;恶心、呕吐;嗳气、善太息;厌油腻;脘闷;大便干结方面,积分均较治疗前有所下降,有统计学差异(P0.01)。结论:1、疏肝和胃降逆法能够改善原发性胆汁反流性胃炎(肝气犯胃证型)患者的中医证候表现。2、疏肝和胃降逆法能够改善原发性胆汁反流性胃炎(肝气犯胃证型)患者的胃镜下炎症病变和胆汁反流情况。
[Abstract]:Objective: to investigate the clinical effect of primary bile reflux gastritis (GG) by using the method of soothing the liver and lowering the stomach. Methods: a total of 50 patients with primary bile reflux gastritis (liver qi and stomach syndrome) were selected from January 2016 to January 2017 in the outpatient clinic of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. 50 patients were treated with the methods of soothing the liver and lowering the inverse of stomach (the main drug composition: Chaihu, Fructus Aurantii, Atractylodes macrocephala, Magnolia officinalis, Atractylodes macrocephala, etc.). The drug was added with water for about 400 ml, soaked for 1 hour, fried for 15-20 minutes, and the juice was taken. Two decoction plus water 400 ml, two decoction mixed, two times warm clothes before early supper, 8 weeks after 8 weeks of treatment, observed the clinical efficacy, symptom score, changes of gastroscope, statistical analysis of the results. Results: the clinical effective rate of primary bile reflux gastritis was 91.49, the total effective rate of treating gastric mucosa was 93.61, the total effective rate of treating bile regurgitation was 95.74 and the total effective rate of TCM syndrome was 91.49. In TCM syndromes total integral, after treatment than before treatment significantly decreased (P0.01). In the single integral of TCM syndromes, after treatment, there are two sides in the patients' stomach pain or pain channeling; epigastric fullness; unobstructed mood; regurgitation, heartburn; bitter mouth, bad breath; nausea, vomiting; belching, good breath; anaerobic greasy; epigastric tightness; stool dryness; The scores were significantly lower than those before treatment (P 0.01). Conclusion the methods of relieving liver and lowering stomach inversion can improve the symptoms of traditional Chinese medicine syndrome of primary bile reflux gastritis (liver qi invading stomach syndrome type), and soothing liver and stomach descending method can improve primary bile reflux gastritis (liver qi invading stomach syndrome type). Inflammation and bile regurgitation under gastroscopy.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

【参考文献】