助阳补肺除痹颗粒治疗慢性阻塞性肺疾病稳定期（肺肾亏虚，寒瘀阻络证）的临床观察

发布时间：2018-06-29 10:40

本文选题：慢阻肺稳定期 + 助阳补肺除痹颗粒　；参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:评价助阳补肺除痹颗粒在中医辨证属于肺肾亏虚,寒瘀阻络证的慢性阻塞性肺疾病稳定期(III级)治疗中的优势,观察其有效性,探寻更好的临床治疗慢性阻塞性肺疾病的方法,从而进一步提高中医药治疗慢性阻塞性肺疾病的临床疗效。方法:将72例来源于长春中医药大学附属医院2014-2015年门诊和疗区,确诊为慢阻肺稳定期(III级)患者的患者,随机分为治疗组和对照组各36例。治疗组用助阳补肺除痹颗粒联合沙美特罗替卡松粉吸入剂(舒利迭)治疗,对照组用沙美特罗替卡松粉吸入剂(舒利迭)治疗,疗程为4周,通过对临床症状、呼吸困难指数、六分钟步行试验以及肺功能前后变化情况的评估,比较治疗组和对照组的疗效差异,最终得出客观的结论。结果:助阳补肺除痹颗粒联合舒利迭组有效率为86.11%,西药对照组有效率为72.22%,两组对比统计学上有明显差异(P0.05),说明治疗组疗效优于对照组疗效。结论:助阳补肺除痹颗粒联合舒利迭能有效地治疗慢阻肺定期(III级),并且较单纯应用舒利迭,能更加有效的缓解慢阻肺咳嗽、喘促、咯痰、畏寒等症状、增加六分钟步行距离、减轻呼吸困难程度,具有更好的临床疗效。
[Abstract]:Objective: to evaluate the advantages of Zhuyang Bufei debi granule in the treatment of chronic obstructive pulmonary disease (class III) with syndrome differentiation of deficiency of lung and kidney and obstruction of collaterals by cold and blood stasis, and to observe its effectiveness. To explore a better clinical treatment of chronic obstructive pulmonary disease, so as to further improve the clinical efficacy of traditional Chinese medicine in the treatment of chronic obstructive pulmonary disease. Methods: Seventy-two patients from the outpatient department and treatment area of Changchun University of traditional Chinese Medicine from 2014 to 2015 were randomly divided into treatment group (n = 36) and control group (n = 36). The treatment group was treated with Zhuyang Bufei debi granule combined with salmeterolticasone powder inhalation (sulide), while the control group was treated with salmeterolticasone powder inhalation (sullide) for 4 weeks. The index of dyspnea was determined by clinical symptoms. The six minute walking test and the evaluation of lung function before and after, the curative effect difference between the treatment group and the control group was compared, and the objective conclusion was reached. Results: the effective rate of the treatment group was 86.11, and that of the western medicine control group was 72.22. There was significant statistical difference between the two groups (P0.05), which indicated that the curative effect of the treatment group was better than that of the control group. Conclusion: the combination of Zhuyang Bufei debi granule and sulipid can effectively treat chronic obstructive pulmonary disease (stage III), and it can relieve cough, asthma, phlegm, chills and other symptoms more effectively, and increase the walking distance of six minutes, compared with the simple application of Shulide, and can effectively relieve the symptoms of chronic obstructive lung, such as cough, shortness of breath, phlegm, chills and so on. Reduce the degree of dyspnea, has a better clinical effect.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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