新疆和田地区维汉两民族慢性阻塞性肺疾病中医证候与西北燥证相关性研究

发布时间：2018-06-30 07:09

本文选题：慢性阻塞性肺疾病 + 新疆和田　；参考：《新疆医科大学》2016年硕士论文

【摘要】：目的:调查分析新疆和田地区维汉两民族慢阻肺患者及对比样本中医证候与西北燥证的罹患情况,探讨新疆慢阻肺的证候特点及其与西北燥证的相关性。方法:1.问卷调查2015年7月间入住和田地区医院、和田市医院的慢阻肺患者作为病例组,共78例;同时按1:2比例,问卷调查和田地区相应社区民族、年龄相同,年龄差别不大于5岁的非慢阻肺(包括非慢阻肺相关性疾病)的健康人群作为对照组,共156例。在两组样本之间开展病例对照研究。2.在两组样本中调查西北燥证罹患率。3.在病例组中调查慢阻肺症状表现,以开展病情指数分析和中医证候类型分析;并收集国内慢阻肺中医辨证论治论文进行文献计量学分析,以衬托新疆慢阻肺的证候特点。4.统计分析中引入病情指数、证情指数、本病指数等计量学指标,并运用卡方检验、方差分析、相关分析和聚类分析等方法。结果:1.新疆和田地区慢阻肺患者西北燥证罹患率(51.28%)显著高于对照组(12.82%),慢阻肺之罹患西北燥证与否的优势比OR值为7.16。2.慢阻肺病人中,其患有西北燥证者之病情指数、证情指数均高于非患者(P0.01或P0.05),前者之病情分级重于后者,而证候构成复杂程度亦大于后者。3.维汉两民族在对照组中西北燥证罹患率有差别,女性西北燥证罹患率高于男性,病例组维族西北燥证罹患率高于汉族,乃因其病情重于汉族所致;病例组维吾尔族患者病情指数、病情分级均高于汉族;汉族之风燥伤肺证情指数大于维族,维族之痰瘀阻肺和外寒内饮证情指数大于汉族;维吾尔族患者之西北燥证主证证情轻于汉族,而其兼证证情则高于汉族。4.性别分析显示,女性慢阻肺西北燥证患者病情重于男性;而无论病例组或对照组,女性病人西北燥证罹患率(55.88%,17.64%)均高于男性(47.72%,9.09%)(P0.05)。5.年龄分析显示,年龄越大,慢阻肺病情指数、证情指数越高,西北燥证罹患率及其证情指数亦高。6.西北燥证主兼证在慢阻肺患者中均可见到,西北燥证之肺心脾风火燥证与慢阻肺之5个证候关系最密切。7.与国内慢阻肺文献相比,新疆慢阻肺稳定期多发症状以口干、口苦、畏寒、痰鸣等出现频次高出国内,而以纳呆、便溏等出现频次低于国内;证候结构比较,两者气虚痰阻、气阴两虚、痰瘀阻肺这3个证候出现频次基本相当,而新疆慢阻肺稳定期的风燥伤肺、肝火犯肺、外寒内饮证候出现频次多于国内;新疆慢阻肺稳定期以外寒内饮为本病证候,而国内本病证候为气虚痰阻。结论:1.新疆和田地区慢阻肺病人西北燥证罹患率高于非罹患者,西北燥证主兼证在和田地区慢阻肺患者均可见到,西北燥证与慢阻肺的罹患关系非常密切,西北燥证之肺心脾风火燥证对慢阻肺影响最大。2.维族慢阻肺患者病情和证情重于汉族,两民族病人证候结构有所不同;男女慢阻肺病人病情差别不显著,但女性较男性易患西北燥证;年龄大者其病情、证情、西北燥证罹患情况较重。3、与国内比较,新疆和田地区慢阻肺稳定期的症状特点是口干、口苦、畏寒、痰鸣等;证候特点是风燥伤肺、肝火犯肺、外寒内饮等这些证候;本病证候为外寒内饮,亦不同于国内。
[Abstract]:Objective: To investigate and analyze the incidence of TCM syndrome and Northwest Dryness Syndrome of the patients with slow resistance lung of the two ethnic groups in Xinjiang and the Hetian region, and to explore the syndrome characteristics of the chronic obstructive pulmonary disease in Xinjiang and the correlation with the Northwest Dryness Syndrome. Methods: 1. questionnaires were conducted to investigate the chronic obstructive pulmonary patients in Hetian hospital in July 2015 and the patients with chronic obstructive pulmonary disease in Hetian hospital as a disease. In a total of 78 cases, a total of 156 cases of non slow resistance lung (including non slow obstructive pulmonary related diseases) were selected as the control group according to the proportion of 1:2 in the corresponding community nationalities, age differences not more than 5 years old (including non slow resistance lung related diseases), and a total of 156 cases were studied in the two groups of samples. The investigation of the Northwest Dryness Syndrome in the two groups of samples was conducted by.2.. Rate.3. was used to investigate the symptoms of chronic obstructive pulmonary disease in the case group, to carry out the analysis of the disease index and the type of TCM syndrome, and to collect the bibliometric analysis of the Chinese traditional Chinese medicine syndrome differentiation for chronic obstructive pulmonary disease, and to introduce the index, the syndrome index, the disease index, and so on in the statistical analysis of the syndrome characteristics of the chronic obstructive pulmonary disease in Xinjiang in the.4. statistical analysis. And using chi square test, analysis of variance, correlation analysis and cluster analysis. Results: 1. the incidence of Northwest Dryness Syndrome (51.28%) in 1. Xinjiang Hetian patients was significantly higher than that of the control group (12.82%). The dominant ratio of the slow resistance lung to northwest dryness was 7.16.2. in the patients with chronic obstructive pulmonary disease, and the disease index of the northwest dryness syndrome was confirmed. The index of the situation was higher than that of the non patients (P0.01 or P0.05), the former was heavier than the latter, and the complexity of the syndrome was more complex than the latter.3. Wei Han nationality. The incidence of dryness syndrome was higher in the control group than in the control group. The incidence rate of the Northwest Dryness Syndrome in the female was higher than that of the male, and the incidence rate of the West North dryness syndrome in the case group was higher than that of the Han nationality, but the disease was heavier than the Han nationality in the case group. The disease index of Uygur patients in the case group is higher than that of the Han nationality, and the index of lung syndrome in the Han nationality is greater than that of the Uygur, and the index of phlegm and blood stasis in the Uygur nationality is greater than that of the Han nationality, and the main syndrome of the Northwest Dryness Syndrome of Uygur patients is less than that of the Han nationality, but the syndrome is higher than the Han.4. sex analysis, and the female is higher than the Han nationality. The incidence of Northwest Dryness Syndrome of sexual slow resistance lung was more serious than that of male, while the incidence rate of Northwest Dryness Syndrome (55.88%, 17.64%) in female patients (55.88%, 17.64%) was higher than that of men (47.72%, 9.09%) (P0.05).5. age analysis showed that the older the age, the more chronic obstructive pulmonary disease index, the higher the index of syndrome, the incidence of Northwest Dryness Syndrome and the higher.6. northwest dryness. The 5 syndromes of the lung, heart, spleen, wind, heat and dryness syndrome of the Northwest Dryness Syndrome and the 5 syndromes of the slow resistance lung were most closely related to the chronic obstructive pulmonary disease in the Northwest Dryness Syndrome. Compared with the domestic slow resistance lung literature, the frequent symptoms in the stable stage of Xinjiang's slow resistance lung were higher than the domestic, while the frequent occurrence frequency of dry mouth, pain, cold and phlegm was higher than the domestic. Syndrome structure comparison, both qi deficiency phlegm resistance, Qi Yin deficiency, phlegm and stagnation of lung these 3 syndrome frequency basically equal, but Xinjiang slow resistance lung stable period of wind dryness lung, liver fire, lung, external cold internal drinking syndrome frequency more frequent than the domestic; Xinjiang slow resistance lung stability outside cold internal drink for this disease syndrome, and domestic syndrome is Qi deficiency phlegm resistance. Conclusion: 1. the incidence of Northwest Dryness Syndrome of chronic obstructive pulmonary patients in Xinjiang Hetian area is higher than that of non patients. The Northwest Dryness Syndrome is very close to the chronic obstructive pulmonary patients in Hetian area. The relationship between the Northwest Dryness Syndrome and the slow resistance lung is very close. The lung, spleen and wind and fire syndrome of the Northwest Dryness Syndrome have the most influence on the slow hindrance lung patients with the slow hindrance of the lung and the syndrome of the.2.. The syndrome structure of the two ethnic group was different, and the difference of the patient's disease was not significant, but the female was more susceptible to the northwest dryness syndrome than the male. The age of the patients with the disease, the syndrome and the northwest dryness syndrome were.3. The symptom characteristics of the stable period of the slow resistance lung in Xinjiang Hetian area were dry mouth, bitter, cold, phlegm and so on. These syndromes are wind dryness, lung injury, liver fire invading the lung, external cold and internal drinking. This syndrome is external cold internal drinking, and also different from domestic.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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