补肾和脉颗粒对老年H型单纯收缩期高血压颈动脉粥样硬化斑块的干预作用

发布时间：2018-07-06 13:48

本文选题：补肾和脉颗粒 + 老年H型高血压　；参考：《山东中医药大学》2016年硕士论文

【摘要】：目的:观察补肾和脉颗粒对老年H型单纯收缩期高血压颈动脉粥样硬化斑块的干预作用。方法:随机选取符合纳入标准的患者70例,随机分为治疗组和对照组两组,每组35例。对照组采用常规西医治疗老年H型单纯收缩期高血压伴颈动脉粥样硬化,治疗组在西医常规治疗的基础上加用补肾和脉颗粒口服,一次两袋,一天两次,四周为一治疗周期。观察患者相关指标在治疗前后的改善情况。结果:对照组与治疗组在治疗前后收缩压值、高血压症状,颈动脉内中膜厚度、颈动脉斑块均有良好的改善,组间疗效无统计学差异,中医症状积分、颈动脉斑块积分(Crouse积分)试验组明显优于对照组(P0.01)。结论:补肾和脉颗粒可以明显降低患者收缩压水平、颈动脉内中膜厚度,减少斑块形成,改善患者的不适症状,提高患者的生活质量,是治疗老年H型单纯收缩期高血压伴颈动脉粥样硬化的有效方剂,值得在临床进一步推广应用。
[Abstract]:Aim: to observe the intervention effect of Bushen Hemai granule on carotid atherosclerotic plaque in elderly patients with H-type simple systolic hypertension. Methods: 70 patients who met the inclusion criteria were randomly divided into two groups: treatment group and control group with 35 cases in each group. The control group was treated with routine western medicine in elderly patients with H type simple systolic hypertension accompanied with carotid atherosclerosis. The treatment group was treated with Bushen and Mai granules on the basis of routine western medicine, two bags once, two times a day, four weeks for a treatment cycle. To observe the improvement of patients' relative indexes before and after treatment. Results: systolic blood pressure (SBP), hypertension symptom, carotid intima media thickness and carotid plaque were all improved in the control group and the treatment group before and after treatment, but there was no significant difference in the curative effect between the two groups. The carotid plaque score (Crouse score) in the experimental group was significantly better than that in the control group (P0.01). Conclusion: Bushen and Mai granule can significantly reduce the systolic blood pressure, carotid intima media thickness, reduce plaque formation, improve the uncomfortable symptoms of patients, improve the quality of life of patients. It is an effective prescription for the treatment of H type simple systolic hypertension with carotid atherosclerosis in the elderly.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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