2500例新发脑梗死疗效的相关影响因素回顾性研究

发布时间：2018-07-06 15:32

本文选题：新发脑梗死 + 多因素　；参考：《南京中医药大学》2017年硕士论文

【摘要】：研究目的:探讨影响新发脑梗死临床疗效的相关因素,并统计分析该疾病发病部位、并发症、中医证型的分布。研究方法:对江苏省中医院2011年1月至2015年12月入院诊断为新发脑梗死2500例患者的病历资料进行回顾性分析,记录并统计既往病史情况、相关生化检查指标、颈部血管彩色超声多普勒结果。根据临床恢复水平分为痊愈、明显改善、改善、无改善及恶化四组,分析各组数据。统计入组患者梗死灶部位,并发症及中医证型。研究结果:对四组新发脑梗死患者性别、吸烟、饮酒、高血压史、糖尿病史、冠心病史、颈部血管斑块进行统计学分析,经卡方检验发现高血压病史及颈部血管斑块具有统计学意义(P0.05),性别、吸烟、饮酒、糖尿病史、冠心病史无统计学意义(P0.05)。对四组患者年龄、舒张压、收缩压、空腹血糖、甘油三酯、总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇以及血尿酸进行统计学分析,经t检验年龄、收缩压、空腹血糖、总胆固醇、血尿酸具有统计学意义(P0.05),舒张压、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇无统计学意义(P0.05)。对单因素分析有统计学差异的因素进行无序logistics分析,发现发现年龄、收缩压、空腹血糖、颈部血管斑块差异具有统计学意义(P0.05且0R值1)。研究结论:患者的年龄、高血压病史、颈部血管斑块、收缩压、空腹血糖、总胆固醇、血尿酸是影响新发脑梗死临床疗效的相关因素,其中年龄、收缩压、空腹血糖及颈部血管斑块是影响新发脑梗死临床疗效的独立危险因素。
[Abstract]:Objective: to investigate the related factors influencing the clinical efficacy of new cerebral infarction, and to analyze the distribution of the disease location, complications and TCM syndromes. Methods: the medical records of 2500 patients with newly diagnosed cerebral infarction from January 2011 to December 2015 in Jiangsu Provincial Hospital of traditional Chinese Medicine were retrospectively analyzed. Color Doppler ultrasonography of cervical blood vessels. According to the clinical recovery level, the patients were divided into four groups: cured group, obvious improvement group, no improvement group and deterioration group. The data of each group were analyzed. The infarct location, complication and TCM syndrome type were counted. Results: sex, smoking, drinking, history of hypertension, history of diabetes, history of coronary heart disease, cervical vascular plaque were statistically analyzed in four groups of patients with newly diagnosed cerebral infarction. Chi-square test found that hypertension history and cervical vascular plaque had statistical significance (P0.05), sex, smoking, alcohol consumption, diabetes history, coronary heart disease history had no statistical significance (P0.05). Age, diastolic blood pressure, systolic blood pressure, fasting blood glucose, triglyceride, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol and serum uric acid were analyzed statistically. Fasting blood glucose, total cholesterol, serum uric acid had statistical significance (P0.05), diastolic blood pressure, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol had no statistical significance (P0.05). Disordered logistics analysis showed that age, systolic blood pressure, fasting blood glucose and cervical vascular plaque had statistical significance (P0.05 and 0R value 1). Conclusion: age, history of hypertension, carotid plaque, systolic blood pressure, fasting blood glucose, total cholesterol, serum uric acid are the related factors that affect the clinical efficacy of new cerebral infarction. Fasting blood glucose and cervical vascular plaque are independent risk factors for clinical efficacy of new cerebral infarction.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.7

【相似文献】