十五种藏药方剂抑菌作用的研究
发布时间:2018-07-08 11:41
本文选题:藏药 + 金黄色葡萄球菌 ; 参考:《黑龙江畜牧兽医》2017年17期
【摘要】:为了探讨清热消炎类藏药方剂对临床常见致病菌的抑菌作用,试验采用琼脂打孔法研究了15种藏药对金黄色葡萄球菌、大肠埃希菌、铜绿假单胞菌、沙门氏菌的抑菌效果,通过倍比稀释法测定部分药物对敏感菌株的最小抑菌浓度(MIC),并绘制帮间久埃作用36 h的细菌生长曲线。结果表明:帮间久埃、仁青芒觉、六味丁香丸、七味红花殊胜丸对金黄色葡萄球菌均有显著抑菌作用,帮间久埃对金黄色葡萄球菌的MIC介于6.25~12.5 mg/m L之间,仁青芒觉、六味丁香丸、七味红花殊胜丸的MIC介于12.5~25 mg/m L之间,但对革兰氏阴性菌的抑菌作用较弱。说明部分藏药方剂对耐药性金黄色葡萄球菌具有明显的抑菌作用。
[Abstract]:In order to study the bacteriostatic effect of Qingre anti-inflammatory Tibetan medicine prescription on common clinical pathogenic bacteria, the bacteriostatic effect of 15 kinds of Tibetan medicine on Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella was studied by Agar perforation method, and the antibacterial effect of 15 kinds of Tibetan medicine against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella were studied. The minimal inhibitory concentration (MIC) of some drugs against sensitive strains was determined by double dilution method, and the growth curve of bacteria exposed to the drug for 36 h was plotted. The results showed that Dianjianjiuai, Ren Qingmanxue, Liuwei eugenia pills and Qiwei safflower Shusheng pills had significant bacteriostatic effect on Staphylococcus aureus. The MIC of Bujianjiuye to Staphylococcus aureus ranged from 6.25 mg/m / L to 12.5 mg/m / L, and the latter was between 6.25 mg/m / L and 12.5 mg/m / L for Staphylococcus aureus, respectively. The MIC of Liuwei eugenia pills and Qiwei safflower Shusheng pills was between 12.5 and 25 mg/m / L, but the bacteriostatic effect on Gram-negative bacteria was weak. It shows that some Tibetan prescriptions have obvious bacteriostatic effect on resistant Staphylococcus aureus.
【作者单位】: 西藏民族大学医学院;咸阳市中心医院;昌都市丁青县嘎塔乡人民政府;山南市扎囊县扎其乡卫生院;拉萨市达孜县章多乡卫生院;
【基金】:西藏自治区自然科学基金项目(2015ZR-13-23) 西藏民族大学校级项目(14my Q14)
【分类号】:R29
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