电针对兔面神经损伤的超微结构影响

发布时间：2018-07-08 14:20

本文选题：电针 + 面神经损伤　；参考：《针刺研究》2017年05期

【摘要】：目的:对比电针与手针对面神经损伤兔面神经雪旺细胞、髓鞘及线粒体等结构形态学影响,探索电针治疗面神经损伤的机制。方法:新西兰兔随机分为正常组、假手术组、模型组、手针组、电针组,每组10只。经面神经压榨复制面神经损伤模型。电针组取"地仓""下关""太阳""阳白"进行电针治疗,每次30min;手针组选穴同电针组,每10min平补平泻捻转手法行针1次,留针30min。两组均每日治疗1次,共治疗28d。每7d进行1次面肌运动评分,28d后电镜观察各组面神经超微结构。结果:治疗后,假手术组与正常组比较各项结果未见明显变化(P0.05)。模型组在面肌运动评分、超微结构形态学变化以及单位面积轴突数目、髓鞘厚度、轴突面积等方面均差于正常组(P0.05);两治疗组面肌运动评分、超微结构形态学变化以及单位面积轴突数目、髓鞘厚度、轴突面积均好于模型组(P0.05);电针组各项结果均好于手针组(P0.05)。结论:在面神经损伤的治疗中,电针比手针更能促进轴浆线粒体增殖、髓鞘恢复以及轴索再生,这可能是电针治疗面神经损伤效果优于手针的机制之一。
[Abstract]:Aim: to compare the morphological effects of electroacupuncture on Schwann cells, myelin sheath and mitochondria of facial nerve in rabbits with facial nerve injury, and to explore the mechanism of electroacupuncture in the treatment of facial nerve injury. Methods: new Zealand rabbits were randomly divided into normal group, sham operation group, model group, hand acupuncture group and electroacupuncture group. Facial nerve injury model was established by facial nerve compression. In the electroacupuncture group, the acupuncture group was treated with electroacupuncture for 30 mins each time, and the acupoints of the hand acupuncture group were selected with the same electroacupuncture group, and the acupuncture was performed once per 10min, and the needle was kept for 30 mins. The acupuncture group was treated with "Dicuang", "Xiaguan" and "Yangbai" for 30 minutes. The two groups were treated once a day for 28 days. Facial nerve ultrastructure was observed by electron microscope every 7 days. Results: after treatment, the sham-operation group and the normal group showed no significant changes in the results (P0.05). The average value of facial muscle motor score, ultrastructural morphology, number of axons per unit area, myelin sheath thickness and axon area in the model group were lower than those in the normal group (P0.05). The morphological changes of ultrastructure, the number of axons per unit area, the thickness of myelin sheath and the area of axons in the model group were better than those in the model group (P0.05), and the results of electroacupuncture group were better than those of the hand acupuncture group (P0.05). Conclusion: in the treatment of facial nerve injury, electroacupuncture can promote mitochondria proliferation, myelin sheath recovery and axonal regeneration more than hand acupuncture, which may be one of the mechanisms of electroacupuncture in treating facial nerve injury better than hand acupuncture.
【作者单位】：青岛市海慈医疗集团;山东中医药大学针灸推拿学院;
【基金】：国家自然科学基金项目(No.81273917)
【分类号】：R245

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