2型糖尿病阴阳两虚证与垂体-甲状腺轴的相关性
发布时间:2018-07-21 16:31
【摘要】:目的:探讨2型糖尿病阴阳两虚证与垂体-甲状腺轴的相关性。方法:将2型糖尿病患者499例分为阴虚热盛、湿热困脾、气阴两虚、阴阳两虚4型。测定患者静脉空腹血糖(FPG)、餐后2小时血糖(2 hPG)、糖化血红蛋白(HbA_(1c))、空腹血清C肽(FCP)、餐后2hC肽(2hPCP)、游离三碘甲状腺原氨酸(FT_3)、游离甲状腺素(FT_4)、促甲状腺激素(TSH)、甲状腺球蛋白(Tg)、甲状腺球蛋白抗体(Tg Ab)、甲状腺过氧化物酶抗体(TPOAb)水平。结果:阴阳两虚型患者的年龄、病程大于其余3型(P0.001);气阴两虚型患者的年龄、病程大于阴虚热盛型(P0.05)。气阴两虚型患者FPG、2h PCP高于阴阳两虚型(P0.05);阴阳两虚型患者FT_3水平低于阴虚热盛型、湿热困脾型、气阴两虚型(P0.01)。阴阳两虚型患者的FT_4水平显著低于气阴两虚型(P0.01)。结论:甲状腺激素水平与2型糖尿病患者阴阳两虚证存在密切相关性。
[Abstract]:Objective: To investigate the correlation between the two deficiency syndrome of type 2 diabetes Yin Yang and the pituitary thyroid axis. Methods: 499 cases of type 2 diabetes were divided into 499 cases of yin deficiency heat, damp heat trapped in spleen, Qi and yin deficiency, yin and yang two deficiency 4. The patient's venous fasting blood glucose (FPG), postprandial 2 hour blood glucose (2 hPG), glycosylated hemoglobin (HbA_ (1c)), fasting serum C peptide (FCP), and postprandial 2hC peptide were measured. (2hPCP) free three iodine thyroxine (FT_3), free thyroxine (FT_4), thyroid stimulating hormone (TSH), thyroid globulin (Tg), thyroid globulin antibody (Tg Ab) and thyroid peroxidase antibody (TPOAb). Results: the age of the patients with Yin and yang deficiency type two, the course of disease is greater than the other 3 types (P0.001); the age of patients with deficiency of Qi and Yin and the course of disease More than Yin deficiency heat type (P0.05). The patients with Qi and yin deficiency type FPG, 2h PCP higher than Yin and yang two deficiency type (P0.05); the FT_3 level of yin and yang deficiency type patients is lower than Yin deficiency heat type, damp heat trapped in spleen type, Qi Yin deficiency type (P0.01). The level of FT_4 in patients with Yin and yang two deficiency is significantly lower than that of Qi Yin two deficiency type (P0.01). Conclusion: thyroid hormone level and type 2 diabetes mellitus patients are significantly lower than that of type 2 diabetes mellitus. There is a close correlation between yin and yang two deficiency syndrome.
【作者单位】: 苏州大学附属第一医院;上海中医药大学附属龙华医院;
【分类号】:R259
本文编号:2136122
[Abstract]:Objective: To investigate the correlation between the two deficiency syndrome of type 2 diabetes Yin Yang and the pituitary thyroid axis. Methods: 499 cases of type 2 diabetes were divided into 499 cases of yin deficiency heat, damp heat trapped in spleen, Qi and yin deficiency, yin and yang two deficiency 4. The patient's venous fasting blood glucose (FPG), postprandial 2 hour blood glucose (2 hPG), glycosylated hemoglobin (HbA_ (1c)), fasting serum C peptide (FCP), and postprandial 2hC peptide were measured. (2hPCP) free three iodine thyroxine (FT_3), free thyroxine (FT_4), thyroid stimulating hormone (TSH), thyroid globulin (Tg), thyroid globulin antibody (Tg Ab) and thyroid peroxidase antibody (TPOAb). Results: the age of the patients with Yin and yang deficiency type two, the course of disease is greater than the other 3 types (P0.001); the age of patients with deficiency of Qi and Yin and the course of disease More than Yin deficiency heat type (P0.05). The patients with Qi and yin deficiency type FPG, 2h PCP higher than Yin and yang two deficiency type (P0.05); the FT_3 level of yin and yang deficiency type patients is lower than Yin deficiency heat type, damp heat trapped in spleen type, Qi Yin deficiency type (P0.01). The level of FT_4 in patients with Yin and yang two deficiency is significantly lower than that of Qi Yin two deficiency type (P0.01). Conclusion: thyroid hormone level and type 2 diabetes mellitus patients are significantly lower than that of type 2 diabetes mellitus. There is a close correlation between yin and yang two deficiency syndrome.
【作者单位】: 苏州大学附属第一医院;上海中医药大学附属龙华医院;
【分类号】:R259
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