除湿止痒汤治疗湿热内蕴型风瘙痒的临床研究

发布时间：2018-07-26 12:26

【摘要】：目的:在中医理论的指导下,通过对“除湿止痒汤”临床治疗效果观察,进一步探讨中医清热利湿、凉血止痒的理论在治疗湿热内蕴型风瘙痒的作用,以确认其安全性和有效性,并观察临床疗效。方法:选择符合纳入标准的风瘙痒门诊患者62例,分为治疗组31例,对照组31例。其中治疗组给予“除湿止痒汤”(由龙胆、黄芩、栀子、板蓝根、白鲜皮、地肤子、生地黄、牡丹皮、忍冬藤,车前草、蒲公英、紫花地丁的免煎颗粒组成)用法:温水冲服200ml,日两剂,早晚分服,每次100ml。对照组给予金蝉止痒颗粒(金银花、白鲜皮、蛇床子、连翘、地肤子、栀子等)用法:饭后开水冲服,一次一袋,一日3次。2周一疗程,连续观察2个疗程。结果:经临床观察结果显示,治疗组总有效率80.65%,对照组总有效率61.29%,治疗组总有效率明显优于对照组,且经统计学分析,P0.05,两组相比差异有统计学意义。治疗组能明显改善患者瘙痒程度、持续时间、发作频次等症状。结论:除湿止痒汤能显著改善泛发性湿热内蕴型风瘙痒的症状及体征,优于金蝉止痒颗粒的临床疗效,且安全有效。
[Abstract]:Objective: under the guidance of traditional Chinese medicine theory, through the clinical treatment effect observation of "dehumidification and itching decoction", to further discuss the effect of the theory of clearing heat and promoting dampness, cooling blood and relieving itching in the treatment of damp-heat endogenous wind pruritus. In order to confirm its safety and effectiveness, and observe the clinical efficacy. Methods: 62 patients with rheumatic pruritus were divided into treatment group (31 cases) and control group (31 cases). The treatment group was given "dehumidification and itching decoction" (by Gentian, Scutellaria baicalensis, Gardenia, Radix Isatidis, White fresh skin, Fructus Dioscorea, Rehmannia Rehmanniae, Peony Peony, Lonicera Lonicera, Plantago plantarum, Dandelion, etc.) Use: warm water to take 200 ml, two doses daily, morning and evening, 100 ml. The control group was given Jincichang Zhiitch granules (honeysuckle, fresh skin, Cnidium nidifolia, Forsythia suspensa, Fructus Forsypium, Gardenia jasminoides, etc.): take boiled water after meals, one bag once a day, two courses of treatment were observed 3 times a day for 2 weeks. Results: the results of clinical observation showed that the total effective rate of the treatment group was 80.65 and the total effective rate of the control group was 61.29. The total effective rate of the treatment group was obviously better than that of the control group, and the statistical analysis showed that the total effective rate of the treatment group was 80.65 and that of the control group was 61.29.The difference between the two groups was statistically significant. Treatment group can significantly improve the degree of itching, duration, attack frequency and other symptoms. Conclusion: dehumidification and itching decoction can significantly improve the symptoms and signs of generalized damp-heat endogenous wind-pruritus, which is superior to Jinchengzhitao granule and is safe and effective.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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