慢性肾小球肾炎本虚与标实证候分布及组合特点研究
发布时间：2018-07-27 15:49
【摘要】：目的研究慢性肾小球肾炎本虚与标实证候分布及组合特点。方法采取问卷调查形式对200例慢性肾小球肾炎患者的临床信息进行采集记录,归纳各中医证候之间的分布和组合情况。观察中医证候要素分布情况,湿热证和血瘀证中医证候组合情况,对湿热证组、血瘀证组、湿热兼血瘀证组3组血白细胞计数(WBC)、血总胆固醇(CHO)、血红蛋白(HGB)、血肌酐(SCr)、尿蛋白定量等各项指标进行比较。结果 200例患者出现的中医证候要素主要有湿热、气虚、血瘀、肝郁气滞、水湿、肝郁化火、阳虚、阴虚、痰浊、外风、肝肾阴虚、阴虚动风,其中本虚证候中以气虚证出现频率最高,标实证候中湿热证和血瘀证的出现频率较高。湿热证组、血瘀证组、湿热兼血瘀证组3组SCr、尿蛋白定量比较差异有统计学意义(P0.05),SCr、尿蛋白定量湿热兼血瘀证组均高于血瘀证组和湿热证组,差异均有统计学意义(P0.05)。结论慢性肾小球肾炎本虚证以气虚证为主,标实证以湿热证、血瘀证为主,湿热和血瘀可能通过某种协同作用加重对正气的耗伤。
[Abstract]:Objective to study the syndromes distribution and combination characteristics of chronic glomerulonephritis. Methods the clinical information of 200 patients with chronic glomerulonephritis was collected and recorded by questionnaire, and the distribution and combination of TCM syndromes were summarized. Observe the distribution of TCM syndromes, the combination of dampness and heat syndrome and blood stasis syndrome, the dampness and heat syndrome group, the blood stasis syndrome group, WBC count (WBC), total cholesterol (CHO), hemoglobin (HGB), serum creatinine (SCr), urine protein quantitative index were compared among the three groups of damp-heat and blood stasis syndrome group. Results the main factors of TCM syndrome in 200 patients were dampness and heat, qi deficiency, blood stasis, liver stagnation and qi stagnation, water dampness, liver depression to turn fire, yang deficiency, yin deficiency, phlegm turbidity, external wind, liver and kidney yin deficiency, yin deficiency moving wind. Qi deficiency syndrome is the most frequent, and dampness and heat syndrome and blood stasis syndrome are higher in standard syndrome. There were significant differences in the levels of SCrand urine protein between the three groups (P0.05). The quantitative differences of urinary protein in the dampness heat and blood stasis syndrome group were higher than those in the blood stasis syndrome group and the damp-heat syndrome group (P0.05). Conclusion chronic glomerulonephritis is characterized by deficiency of qi, damp-heat syndrome and blood stasis syndrome. Dampness and heat and blood stasis may aggravate the consumption of positive qi through some synergistic effect.
【作者单位】： 中国中医科学院广安门医院(南区);北京中医药大学东直门医院;中国中医科学院西苑医院;北京中医药大学;首都医科大学附属北京中医医院;
【分类号】：R277.5
[Abstract]:Objective to study the syndromes distribution and combination characteristics of chronic glomerulonephritis. Methods the clinical information of 200 patients with chronic glomerulonephritis was collected and recorded by questionnaire, and the distribution and combination of TCM syndromes were summarized. Observe the distribution of TCM syndromes, the combination of dampness and heat syndrome and blood stasis syndrome, the dampness and heat syndrome group, the blood stasis syndrome group, WBC count (WBC), total cholesterol (CHO), hemoglobin (HGB), serum creatinine (SCr), urine protein quantitative index were compared among the three groups of damp-heat and blood stasis syndrome group. Results the main factors of TCM syndrome in 200 patients were dampness and heat, qi deficiency, blood stasis, liver stagnation and qi stagnation, water dampness, liver depression to turn fire, yang deficiency, yin deficiency, phlegm turbidity, external wind, liver and kidney yin deficiency, yin deficiency moving wind. Qi deficiency syndrome is the most frequent, and dampness and heat syndrome and blood stasis syndrome are higher in standard syndrome. There were significant differences in the levels of SCrand urine protein between the three groups (P0.05). The quantitative differences of urinary protein in the dampness heat and blood stasis syndrome group were higher than those in the blood stasis syndrome group and the damp-heat syndrome group (P0.05). Conclusion chronic glomerulonephritis is characterized by deficiency of qi, damp-heat syndrome and blood stasis syndrome. Dampness and heat and blood stasis may aggravate the consumption of positive qi through some synergistic effect.
【作者单位】： 中国中医科学院广安门医院(南区);北京中医药大学东直门医院;中国中医科学院西苑医院;北京中医药大学;首都医科大学附属北京中医医院;
【分类号】：R277.5
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