SF-36联合HAMD量表评价益心解郁汤加减治疗心力衰竭后轻度抑郁的作用

发布时间：2018-07-27 20:01

【摘要】：目的:用SF-36联合HAMD量表评价益心解郁汤加减对心衰后轻度抑郁患者的干预作用。方法:将90例心衰后轻度抑郁患者随机分为对照组、舍曲林组及益心解郁汤组。三组均给予常规抗心衰基础治疗,后两组分别加用舍曲林、益心解郁汤加减持续治疗8周。以治疗前后临床疗效、SF-36量表评分及HAMD量表评分变化作为主要观察指标。结果:益心解郁汤组总有效率显著高于对照组,SF-36量表分值均优于对照组(P0.05),HAMD量表评分显著低于对照组(P0.05)。结论:益心解郁汤能改善心衰后轻度抑郁患者的生活质量及抑郁症状,具有较好的临床疗效及安全性。
[Abstract]:Aim: to evaluate the intervention effect of Yixin Jieyu decoction (YXJU) on mild depression after heart failure by SF-36 and HAMD. Methods: 90 patients with mild depression after heart failure were randomly divided into control group, sertraline group and Yixin Jieyu decoction group. The three groups were treated with routine basic therapy of heart failure, the latter two groups were treated with sertraline and Yixin Jieyu decoction for 8 weeks. The changes of SF-36 scale and HAMD scale before and after treatment were taken as the main indexes. Results: the total effective rate of Yixin Jieyu decoction group was significantly higher than that of control group (P0.05). Conclusion: Yixin Jieyu decoction can improve the quality of life and depressive symptoms of patients with mild depression after heart failure.
【作者单位】：浙江中医药大学附属第三医院内科;浙江省立同德医院第二门诊部;浙江中医药大学附属第二医院临床精神卫生科;
【基金】：浙江省中医药科学研究基金项目(2014ZB055) 浙江中医药大学附属第三医院院级项目(2S13YA01)
【分类号】：R259

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