芪术益气汤治疗中老年慢性功能性便秘（气血亏虚证）的临床研究
发布时间：2018-07-28 16:09
【摘要】：目的:观察芪术益气汤治疗中老年慢性功能性便秘中辨证为气血亏虚证的临床疗效,为治疗慢性功能性便秘提供临床参考。方法:选择中老年患者中符合气血亏虚证的慢性功能性便秘诊断标准的病例60例,将其随机分成试验组30例及对照组30例。两组患者于治疗前在性别、年龄、病程、治疗前病情严重程度、中医症候总积分等方面均无统计学差异。试验组给予自拟中药芪术益气汤,水煎至400ml,分早晚两次温服,日一剂;对照组给予口服聚乙二醇4000散(商品名称:福松,规格:10g/袋),口服,1袋/次,2次/日。服药时间均为4周,用药时间结束后4周随访,观察治疗后、治疗后4周中医症候总积分疗效、复发率及安全性。两组患者于治疗前后、治疗后4周的结果用统计学方法分析和处理,并进行组内、组间的比较。结果:临床研究观察显示,试验组痊愈4例,显效15例,有效9例,无效2例,总有效率为93.33%;对照组痊愈1例,显效10例,有效13例,无效6例,总有效率为80.00%;在中医症候总积分方面,两组于治疗后、治疗后4周均较治疗前有显著改善(P0.01),治疗后的改善均显著优于治疗后4周(P0.01);治疗后,试验组中医症候总积分的改善优于对照组(P0.05),提示治疗后在中医症候总积分疗效上试验组优于对照组;治疗后4周,两组在中医症候总积分方面的改善无统计学差异(P0.05);治疗后4周,对两组患者中治疗疗效为痊愈、显效及有效者随访并进行中医症状评分,中医症候总积分治疗结束后4周较治疗前≥50%者即为复发,试验组复发率为32.14%,对照组复发率为50.00%,经统计学方法分析,两组于治疗后4周的远期疗效无统计学差异(P0.05)。此次临床应用芪术益气汤治疗过程中,未发现明显不良反应。结论:芪术益气汤治疗气血亏虚证的中老年慢性功能性便秘有较好的临床疗效,可明显改善患者的临床症状,提高患者的生活质量。
[Abstract]:Objective: to observe the clinical effect of Qizu Yiqi decoction in treating senile chronic functional constipation with syndrome differentiation as deficiency of qi and blood and to provide clinical reference for the treatment of chronic functional constipation. Methods: sixty cases of chronic functional constipation with deficiency of qi and blood were randomly divided into experimental group (n = 30) and control group (n = 30). There was no significant difference between the two groups in sex, age, course of disease, severity of illness before treatment, total score of TCM symptoms and so on. The experimental group was given Qizu Yiqi decoction, a self-made Chinese medicine, fried to 400ml, divided into morning and evening warm clothes, one dose per day, while the control group was given oral polyethylene glycol 4000 powder (commodity name: Fusong, size: 10 g / bag), oral 1 bag per day, 2 times a day. All the patients were treated for 4 weeks, followed up for 4 weeks after the end of the medication. The total integral effect, recurrence rate and safety of TCM symptoms were observed 4 weeks after treatment. Two groups of patients before and after treatment, 4 weeks after treatment with statistical analysis and treatment of results, and carry out intra-group, inter-group comparison. Results: clinical observation showed that 4 cases were cured, 15 cases were effective, 9 cases were effective, 2 cases were ineffective, and the total effective rate was 93.33g in the experimental group, while in the control group, 1 case was cured, 10 cases were markedly effective, 13 cases were effective, 6 cases were ineffective. The total effective rate was 80.00.The total score of TCM symptoms in both groups was significantly improved 4 weeks after treatment (P0.01), and the improvement after treatment was significantly better than that after treatment (P0.01). The improvement of the total integral of TCM symptoms in the experimental group was better than that in the control group (P0.05), suggesting that the experimental group was superior to the control group in the curative effect of the total integral of TCM syndrome after treatment, and 4 weeks after treatment, There was no significant difference in the improvement of the total integral of TCM symptoms between the two groups (P0.05). 4 weeks after treatment, the curative effect of the two groups was cured, marked and effective, followed up with TCM symptom score. The recurrence rate of the experimental group was 32.14 and that of the control group was 50.0.The long-term curative effect of the two groups was not significantly different after 4 weeks of treatment (P0.05). The clinical application of Qizhu Yiqi decoction treatment process, no obvious adverse reactions. Conclusion: Qizhu Yiqi decoction has good clinical effect in treating chronic functional constipation with deficiency of qi and blood. It can obviously improve the clinical symptoms and improve the quality of life of the patients.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.35
本文编号：2150839
[Abstract]:Objective: to observe the clinical effect of Qizu Yiqi decoction in treating senile chronic functional constipation with syndrome differentiation as deficiency of qi and blood and to provide clinical reference for the treatment of chronic functional constipation. Methods: sixty cases of chronic functional constipation with deficiency of qi and blood were randomly divided into experimental group (n = 30) and control group (n = 30). There was no significant difference between the two groups in sex, age, course of disease, severity of illness before treatment, total score of TCM symptoms and so on. The experimental group was given Qizu Yiqi decoction, a self-made Chinese medicine, fried to 400ml, divided into morning and evening warm clothes, one dose per day, while the control group was given oral polyethylene glycol 4000 powder (commodity name: Fusong, size: 10 g / bag), oral 1 bag per day, 2 times a day. All the patients were treated for 4 weeks, followed up for 4 weeks after the end of the medication. The total integral effect, recurrence rate and safety of TCM symptoms were observed 4 weeks after treatment. Two groups of patients before and after treatment, 4 weeks after treatment with statistical analysis and treatment of results, and carry out intra-group, inter-group comparison. Results: clinical observation showed that 4 cases were cured, 15 cases were effective, 9 cases were effective, 2 cases were ineffective, and the total effective rate was 93.33g in the experimental group, while in the control group, 1 case was cured, 10 cases were markedly effective, 13 cases were effective, 6 cases were ineffective. The total effective rate was 80.00.The total score of TCM symptoms in both groups was significantly improved 4 weeks after treatment (P0.01), and the improvement after treatment was significantly better than that after treatment (P0.01). The improvement of the total integral of TCM symptoms in the experimental group was better than that in the control group (P0.05), suggesting that the experimental group was superior to the control group in the curative effect of the total integral of TCM syndrome after treatment, and 4 weeks after treatment, There was no significant difference in the improvement of the total integral of TCM symptoms between the two groups (P0.05). 4 weeks after treatment, the curative effect of the two groups was cured, marked and effective, followed up with TCM symptom score. The recurrence rate of the experimental group was 32.14 and that of the control group was 50.0.The long-term curative effect of the two groups was not significantly different after 4 weeks of treatment (P0.05). The clinical application of Qizhu Yiqi decoction treatment process, no obvious adverse reactions. Conclusion: Qizhu Yiqi decoction has good clinical effect in treating chronic functional constipation with deficiency of qi and blood. It can obviously improve the clinical symptoms and improve the quality of life of the patients.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.35
【参考文献】
相关期刊论文 前10条
1 张虹;刘保延;;功能性便秘的病因研究[J];河南中医;2014年07期
2 廖奕;刘诗;;慢性功能性便秘病理生理机制研究[J];临床消化病杂志;2013年04期
3 安明伟;熊腊根;;生物反馈训练配合针刺疗法治疗功能性便秘30例[J];世界中医药;2013年05期
4 张倩;陈继红;俞媛洁;李孔玲;谭诗云;谭椺;;生物反馈治疗国人功能性便秘效果的Meta分析[J];武汉大学学报(医学版);2013年01期
5 刘绍能;蔡冬;燕东;吴红梅;刘慧敏;;功能性便秘中医证候分布与焦虑抑郁相关性研究[J];中国中医药信息杂志;2011年02期
6 李延青;于岩波;;功能性便秘的诊断与治疗[J];中国实用内科杂志;2011年02期
7 董恒;高玉中;;益气润肠汤治疗慢传输型便秘60例[J];江西中医药;2009年08期
8 黄玲;陈碧芬;;车前番泻颗粒治疗慢性功能性便秘疗效观察[J];临床军医杂志;2009年04期
9 任宏兵;;“提壶揭盖”法治疗慢性功能性便秘[J];辽宁中医杂志;2009年06期
10 郭慧君;王知佳;;中医辨证分型治疗老年功能性便秘80例[J];河北中医;2009年05期
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