中药序贯疗法治疗肾虚血瘀型原发性痛经的临床观察

发布时间：2018-08-02 10:09

【摘要】：目的：运用中药序贯疗法对肾虚血瘀型原发性痛经进行干预,观察中药周期序贯疗法治疗原发性痛经的临床疗效,探讨其作用机制,并分别从补肾调周法及中西医角度阐明其作用机理,为进一步临床推广、应用提供依据。方法：将40例符合纳入病例标准的肾虚血瘀型原发性痛经患者随机分为治疗组20例,对照组20例。治疗组以补肾助阳／温经止痛序贯,对照组为桂枝茯苓胶囊／散结镇痛胶囊,治疗3个月经周期后,进行治疗前后的疗效对比,及对临床中医症候及痛经症状、总有效率、血清性激素水平(P、E2)、血液流变学情况等各项指标有无改善。结果：本研究所观察的治疗组20例肾虚血瘀型原发性痛经的病患经过一个疗程的治疗后,总有效率达到80.0%；治疗以后患者的中医证侯、痛经症状、血液流变学指标、血清性激素指数等,相较于治疗前均有明显的改善。结论：1.补肾助阳/温经止痛序贯疗法可以改善肾虚血瘀型原发性痛经患者的中医症候及痛经症状,是一种安全、有效的治疗方法,值得推广运用和进一步研究。2.补肾助阳／温经止痛序贯疗法可以改善肾虚血瘀型PD患者的血液流变学状态,血清中雌孕激素的含量,改善内分泌情况。在此基础上,甚至可以对此类患者的黄体功能不全、排卵障碍有进一步的调节作用,这值得我们进一步探索。
[Abstract]:Objective: to observe the clinical effect of periodic sequential therapy of traditional Chinese medicine on primary dysmenorrhea of kidney deficiency and blood stasis type, and to explore its mechanism. And from the point of view of tonifying the kidney and regulating the week, and expounding the mechanism of its action, it provides the basis for further clinical popularization and application. Methods: 40 cases of primary dysmenorrhea with kidney deficiency and blood stasis were randomly divided into treatment group (n = 20) and control group (n = 20). The treatment group was followed by tonifying kidney and helping yang / warming meridian to relieve pain, while the control group was Guizhi Fuling capsule / Sanjie analgesia capsule. After 3 menstrual cycles, the curative effect was compared before and after treatment, and the total effective rate of TCM symptoms and dysmenorrhea symptoms was obtained. Serum sex hormone level (Pe 2), hemorheology and other indicators have been improved. Results: the total effective rate of 20 patients with primary dysmenorrhea of kidney deficiency and blood stasis type was 80.0 after one course of treatment, and the TCM syndromes, dysmenorrhea symptoms and hemorheology indexes of the patients after treatment. Serum sex hormone index was significantly improved compared with that before treatment. Conclusion 1. The sequential therapy of tonifying kidney and helping yang / warming the meridian to stop pain can improve the symptoms of TCM and dysmenorrhea in patients with primary dysmenorrhea of kidney deficiency and blood stasis. It is a safe and effective treatment method, which is worth popularizing and further studying. The sequential therapy of tonifying kidney and helping yang / warming the meridian and relieving pain can improve the hemorheology state of PD patients with kidney deficiency and blood stasis, the content of estradiol and progesterone in serum, and improve the endocrine state. On this basis, it can even regulate the luteal dysfunction and ovulation disorder in these patients, which is worthy of further exploration.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.113

【相似文献】