消痞益肠方治疗糖尿病结肠传输障碍的临床研究

发布时间：2018-08-04 20:15

【摘要】：目的:观察消痞益肠方对糖尿病结肠慢传输性便秘患者症候积分、结肠传输时间(CTT)的影响。方法:80例患者随机分为两组,观察组口服消痞益肠方、对照组口服枸橼酸莫沙必利,治疗4周,测定两组治疗前后症候积分、CTT。结果:两组患者各自治疗前后比较,治疗后症候积分、CTT较治疗前均有明显改善(P0.01);两组组间比较,总有效率、CTT无统计学差异(P0.05),对症候积分的改善,观察组优于对照组(P0.05);两组治疗有效患者3个月后复发情况比较,观察组复发率明显低于对照组(P0.05)。结论:结肠传输试验作为糖尿病结肠动力障碍的诊断、治疗评价的检测方法简便安全,消痞益肠方可明显改善糖尿病结肠传输障碍临床症状,缩短结肠传输时间,并减少症状复发。
[Abstract]:Aim: to observe the effect of Xiaopi Yichang recipe on symptom score and colon transit time (CTT) of diabetic patients with slow transit constipation. Methods 80 patients were randomly divided into two groups. The observation group was treated with Xiaopi Yichang decoction and the control group with mosapride citrate for 4 weeks. Results: compared with before and after treatment, the symptom score and CTT of the two groups were significantly improved (P0.01), the total effective rate of CTT had no statistical difference between the two groups (P0.05), and the improvement of the symptom score was not significant between the two groups (P0.05). Observation group was superior to control group (P0.05); the recurrence rate of observation group was significantly lower than that of control group (P0.05). 3 months after treatment, the recurrence rate of observation group was significantly lower than that of control group (P0.05). Conclusion: colonic transit test is a simple and safe method for the diagnosis of diabetic colonic motility disorder. Xiaopi Yichang decoction can obviously improve the clinical symptoms of diabetic colonic transit disorder and shorten the colonic transit time. And reduce the recurrence of symptoms.
【作者单位】：华北理工大学附属医院放射科;唐山市中医医院内分泌2科;
【基金】：河北省中医药管理局科研计划项目(2013256)
【分类号】：R259

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