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淋巴瘤患者症状特征与中医辨证的临床研究

发布时间:2018-08-06 08:20
【摘要】:目的:运用测评量表对单纯中医药治疗阶段的淋巴瘤患者症状进行研究,探索其症状特征及中医证型特点。方法:采用肿瘤常见症状及Anderson中医症状调查量表(MDASI-TCM)进行问卷调查;中医证型诊断标准参照《恶性肿瘤中医诊疗指南》中淋巴瘤一章中医辨证分型部分。对40例处于单纯中医药治疗阶段的淋巴瘤患者进行横断面调查,调查结果运用SPSS 20.0软件对数据进行统计分析,多组独立样本秩和检验分析比较不同证类对生活的干扰程度。结果:淋巴瘤患者普遍存在多种症状,其中发生频率最显著的3个症状为口干(65.00%)、疲劳(62.50%)、睡眠不安(62.50%),症状强度最显著的3个症状分别是疲劳(3.10±2.99)、出汗(2.80±2.98)、口干(2.30±2.58);淋巴瘤患者辨证常出现两证(37.5%)或三证(25.0%)相兼的情况;在证型频次中,虚实夹杂证出现最多,占45.0%,其次为虚证,占42.5%,实证较少,仅占12.5%;虚实夹杂证类患者对一般活动、情绪、生活乐趣方面影响程度大于单纯实证类及虚证类。结论:淋巴瘤患者的症状及证型特点较为复杂,临床大夫在根据患者当前症状表现进行辨证用药的同时,可参照淋巴瘤不同分期、病理类型及ECOG下不同症状的发生情况,为患者进行预防性用药或康复指导。
[Abstract]:Objective: to study the symptoms of lymphoma patients treated with traditional Chinese medicine (TCM) and to explore the characteristics of symptoms and syndromes. Methods: the common symptoms of tumor and Anderson Chinese Medicine symptom Survey scale (MDASI-TCM) were used to investigate the symptoms, and the diagnosis criteria of TCM syndromes referred to the part of TCM syndrome differentiation and classification in the chapter of Chinese Medicine Syndrome differentiation and Classification of Lymphoma in the Guide of diagnosis and treatment of malignant tumor. A cross-sectional investigation was carried out in 40 cases of lymphoma patients in the stage of treatment with traditional Chinese medicine. The results were statistically analyzed by SPSS 20.0 software, and the degree of interference of different syndromes to life was compared by rank sum test of multiple independent samples. Results: there are many symptoms in patients with lymphoma. The three most frequent symptoms were dry mouth (65.00%), fatigue (62.50%), restlessness of sleep (62.50%), fatigue (3.10 卤2.99), sweating (2.80 卤2.98), dry mouth (2.30 卤2.58). In the frequency of syndromes, deficiency and solid inclusion syndrome appeared most, accounting for 45.0, followed by deficiency syndrome, accounting for 42.5, empirical less, only 12.5; the influence degree on general activity, emotion and life fun of patients with deficiency and solid inclusion syndrome was greater than that of pure empirical syndrome and deficiency syndrome. Conclusion: the characteristics of symptoms and syndromes in patients with lymphoma are more complicated. According to the current symptoms of the patients, the clinicians can refer to the different stages, pathological types and the occurrence of different symptoms under ECOG. Give preventive medication or rehabilitation guidance to patients.
【作者单位】: 中国中医科学院广安门医院肿瘤科;
【基金】:中医药行业科研专项(No.201307006) 国家国际科技合作专项(No.2013DFA325)~~
【分类号】:R273

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